28 citations,
April 2008 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
34 citations,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
74 citations,
May 2004 in “Journal of Clinical Hypertension” Minoxidil effectively treats severe hypertension, but watch for side effects.
40 citations,
July 2011 in “The journal of clinical hypertension” Hydralazine and minoxidil are blood pressure medications that relax blood vessels, with potential side effects like rapid heartbeat and fluid retention, and are used for severe or pregnancy-related hypertension.
11 citations,
May 2007 in “Journal of Hypertension” Minoxidil effectively lowers blood pressure in resistant cases, but needs beta-blocker and diuretic support.