Alopecia Types, Current and Future Treatment

This review outlines the historical and ongoing evolution in understanding and treating alopecia areata, highlighting current research frontiers in genetics, immune mechanisms, and potential new treatments, but reports no new results.

This paper discusses anagen effluvium, a reversible non-scarring hair loss often triggered by certain chemotherapy drugs, but presents no new clinical results.

This systematic review suggests that topical ketoconazole may improve hair regrowth and thickness in both animal and human studies for androgenetic alopecia, but further randomized controlled trials are needed.

In this study, researchers found that flavonoid glycosides extracted from Dicerocaryum senecioides leaves significantly promoted hair growth in BalB/c mice, with the shortest hair growth completion time of 19 days compared to the control's 29 days, and dose-dependent results.

This review discusses the potential of herbal treatments like Saw palmetto, Green tea, and Rosemary as alternatives to conventional drugs for androgenetic alopecia, noting that these herbs may inhibit the 5-alpha-reductase enzyme and reduce hair loss with fewer side effects.

Changing hairstyles can help hair regrow in children with hair loss from tight braids or ponytails.

This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.

This study reviewed eight studies investigating transcutaneous drug delivery via fractional laser and microneedling for alopecia treatment, with six studies showing improved hair regrowth over topical therapy alone, suggesting its potential as a promising treatment strategy, although further research is needed to refine treatment parameters.

In this study, sodium thiosulfate was observed to promote hair growth in mice by encouraging hair follicles to enter the growth phase and complementing the effects of minoxidil, suggesting potential benefits for hair loss treatment.

This review discusses various biologics for hair aging but reports no agent capable of reversing the natural aging process of hair.

This review discusses the causes and diagnosis of traction alopecia, emphasizing education for high-risk populations as there is currently no cure, and presents no new clinical findings.

This article reviews current and emerging treatments for alopecia areata, including Janus kinase inhibitors, highlighting variability in clinical outcomes and the lack of sustained remission.

This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.

This review examines current and emerging treatments for androgenetic alopecia and alopecia areata, noting no new results, and highlights promising approaches like novel drug combinations and gene therapy.

In this study, researchers used genetic data from over 52,000 men to identify over 250 genetic loci associated with severe hair loss and developed a predictive algorithm for determining hair loss risk.

This article reviews trichotillomania, highlighting its differences from OCD and recommending treatments like habit reversal therapy and specific medications, but reports no new clinical results.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

In this animal study, researchers found that cedrol, a constituent from Platycladus orientalis, significantly promoted hair growth in a dose-dependent manner in female C57BL/6 mice, surpassing results from blank control and 2% minoxidil groups over 21 days.

This study found that lavender oil significantly promoted hair growth in female C57BL/6 mice by increasing hair follicle number, depth, and dermal thickness, while reducing mast cell numbers.

This paper discusses the potential relationship between finasteride's adverse effects and factors like hand preference and sexual orientation, suggesting these could influence risk in male androgenic alopecia treatment, but reports no new clinical results.

This article reviews current research on animal models for hair regrowth treatments and reports no new findings; it highlights the need for studies comparing therapy efficiency and long-term safety.

In this study, Korean Red Ginseng showed protective effects against chemotherapy-induced premature hair follicle aging in an in vitro model by modulating specific cellular protein expressions.

This study found that the Stem Cell Educator therapy improved hair regrowth and quality of life in patients with severe alopecia areata by restoring immune balance and protecting hair follicles from autoimmune damage.

This study suggests that oxidative stress may contribute to androgenetic alopecia by inducing premature senescence and secretion of hair growth inhibitors in dermal papilla cells from balding scalp.

This review summarizes the current genetic research on alopecia areata, including potential new therapeutic strategies, but reports no new clinical findings.

In this study, telogen effluvium was commonly found to be associated with iron-deficiency anemia and hypothyroidism among female patients in Makkah, Saudi Arabia.

This study found that the MorrF topical solution combination showed significantly better hair growth improvements than Minoxidil alone in male patients with Androgenetic Alopecia.

This article explores the dynamic and energy-efficient nature of telogen hair follicles, challenging the notion of dormancy, and highlights their potential in advancing treatments for hair growth disorders.

This review discusses emerging treatments and mechanisms for alopecia, highlighting potential therapies like janus kinase inhibitors and advances in stem-cell technology, but reports no new experimental results.

This study found that increased dihydrotestosterone levels were observed in both androgenetic alopecia patients and controls, suggesting that follicle sensitivity to DHT may be more critical than DHT levels for alopecia development.

This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.

This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.

This review discusses the current therapeutic options for female pattern hair loss and emphasizes the need for managing patient expectations of permanent regrowth, reporting no new clinical results.

This review outlines the mechanisms, clinical features, and management strategies for alopecia areata and presents no new experimental findings.

This case report suggests that zinc supplements may be necessary to improve hair loss in hypothyroidism patients being treated with thyroxine.

This review discusses the causes, clinical presentation, and management of anagen effluvium, emphasizing its psychological impact and the need for empathy and practical support, but reports no new results.

This article reviews recent advancements in understanding and treating androgenetic alopecia, focusing on new genetic insights, stem cell roles, and diagnostic tools, without reporting new clinical results.

This study found that bimatoprost stimulated hair growth in both human scalp follicle cultures and mouse pelage in vivo, suggesting it might offer a promising treatment for scalp alopecias.

In this study, 68% of patients treated with finasteride showed improved hair growth in male androgenetic alopecia, compared to 38% with Serenoa repens, indicating finasteride's superior efficacy.

This study found that topical Rosmarinus officinalis leaf extract improved hair regrowth in mice and inhibited androgen-associated mechanisms involved in hair loss.

This review describes minoxidil's hair regrowth mechanism and discusses dermatological applications, but reports no new clinical results, emphasizing the need for regular use and addressing allergic reactions.

This review discusses various therapeutic agents for alopecia areata, categorized by efficacy and safety, and highlights the lack of curative treatments and long-term outcome studies.

This review discusses treatments for chemotherapy-induced alopecia, highlighting scalp cooling for hair loss prevention and 2% topical minoxidil for regrowth acceleration as effective options, but reports a need for more rigorous trials to validate promising new therapies.

This review discusses the causes of alopecia, including androgenetic alopecia, and potential active ingredients for hair regrowth, but it does not report new clinical results.

This review discusses recent advancements in hair rejuvenation strategies and assesses the potential of herbal drugs as safer alternatives, but reports no new clinical results.

This study found that Zizyphus jujuba essential oil enhanced hair growth in mice, with the 1% and 10% concentrations showing increased hair length compared to control.

This study found that a series of three monthly courses of medium-dose prednisolone pulse therapy was effective and well tolerated in most patients with active, multifocal alopecia areata but not in those with totalis/universalis.

This article reviews complications associated with modern hair transplant surgery and discusses their treatment and prevention but reports no new clinical results.

This study found that finasteride 1 mg daily, taken before and after hair transplant surgery, significantly improved scalp hair coverage and density in men with androgenetic alopecia compared to placebo.

This review analyzes the clinical, histopathological, and etiopathogenic aspects of alopecia areata and discusses current treatments, reporting no new clinical results.

This article reviews the historical developments in understanding and treating male pattern hair loss, emphasizing the role of dihydrotestosterone and 5α-reductase inhibitors, but reports no new clinical findings.

This study found that the petroleum ether extract from the leaves of Hibiscus rosa-sinensis demonstrated more effectiveness in promoting hair growth in rats compared to the extract from its flowers.

This review discusses current and emerging drug therapies for treating androgenetic alopecia and alopecia areata, and reports no clinical results; it highlights a need for improved and novel treatments.

This study found that a 70% ethanolic extract from Ginkgo biloba leaves promotes hair regrowth in C3H mice.