Zinc Deficiency Associated with Hypothyroidism: An Overlooked Cause of Severe Alopecia

The document discussed the relationship between hypothyroidism and zinc deficiency as a cause of severe alopecia. It highlighted that while hypothyroidism is a known cause of diffuse hair loss, zinc is crucial for thyroid hormone synthesis, and its deficiency can lead to hypothyroidism. Additionally, thyroid hormones are necessary for zinc absorption, creating a cycle where hypothyroidism can cause zinc deficiency. The study demonstrated that hair loss due to hypothyroidism might not improve with thyroxine treatment alone unless zinc supplements are also provided.