Comparative Analysis of 3D and 2D Cell-Culturing Methods in Hair Follicle Spheroid Morphogenesis and Drug Responsiveness

    July 2025 in “ Biomaterials Advances ”
    Justin Tan, Win Lwin Thuya, Hongyu Zhu … Lifeng Kang
    Studysummary This study investigated how 2D and 3D cell culturing methods influence hair follicle morphogenesis, finding that 3D cultures responded more expectedly to minoxidil while 2D cultures reacted better to DHT treatment, challenging the assumption that 3D cultures are always superior.
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    Research cited in this study 30

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