Early Onset Female Pattern Hair Loss: A Case-Control Study for Analyzing Clinical Features and Genetic Variants

    February 2022 in “ Journal of Dermatological Science ”
    Jungyoon Ohn, Ho Young Son, Da Yu … Oh Sang Kwon
    Studysummary This study identified clinical features and genetic variants associated with early onset female pattern hair loss, highlighting decreased hair shaft density and specific SNPs related to androgenic features.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 34

    1. Female Pattern Hair Loss in Men: A Distinct Clinical Variant of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2020
    2. Spironolactone for Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2020
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    7. Peroxisome Proliferator-Activated Receptor-Gamma Mediated Signaling Regulates Mitochondrial Energy Metabolism in Human Hair Follicle Epithelium Journal of Investigative Dermatology · 2018
    8. Genetics and Other Factors in the Etiology of Female Pattern Hair Loss Experimental Dermatology · 2017
    9. A Comparison of the Hormonal Profile of Early Androgenetic Alopecia in Men With the Phenotypic Equivalent of Polycystic Ovarian Syndrome in Women JAMA Dermatology · 2016
    10. A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features Nature Communications · 2016
    11. Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population Dermatology · 2016
    12. Association of Single Nucleotide Polymorphisms in the CYP19A1 Gene with Female Pattern Hair Loss in a Chinese Population Dermatology · 2015
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    20. Investigation of the Male Pattern Baldness Major Genetic Susceptibility Loci AR/EDA2R and 20p11 in Female Pattern Hair Loss British Journal of Dermatology · 2012
    21. Association Analysis of Estrogen Receptor Beta Gene (ESR2) Polymorphisms with Female Pattern Hair Loss British Journal of Dermatology · 2011
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    25. Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss British Journal of Dermatology · 2009
    26. Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia American Journal of Pathology · 2007
    27. Androgenetic Alopecia in Adolescents: A Report of 43 Cases Journal of Dermatology · 2006
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    2. Early Onset Female Pattern Hair Loss: A Case-Control Study for Analyzing Clinical Features and Genetic Variants Journal of Dermatological Science · 2022
    3. Hair Disorders Oxford University Press eBooks · 2018
    4. Hair Loss (Alopecia or Baldness) 2018
    5. Differential Diagnosis of Scalp Hair Folliculitis PubMed · 2011
    6. Male Pattern Baldness: An Update Revista de Ciências Médicas · 2009
    7. Hair and Scalp Diseases CRC Press eBooks · 2008
    8. The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals Brazilian Journal of Medical and Biological Research · 2003
    9. Diseases of the Hair and Scalp Archives of Dermatology · 1994
    10. Dermatologic Clinics: Hair Disorders Archives of Dermatology · 1988