Female Pattern Hair Loss in a Patient with 17α-Hydroxylase Deficiency

January 2010 in “ Acta dermato-venereologica ”

Hsien-Yi Chiu, Sung-Jan Lin

female pattern hair loss 17a-hydroxylase deficiency miniaturization of hairs anagen hairs androgen hyperandrogenaemia FPHL

TLDR Low androgen levels can still cause female pattern hair loss.

This document is a case report of a 20-year-old woman with 17a-hydroxylase deficiency who presented with female pattern hair loss (FPHL). FPHL is characterized by hair loss primarily on the top of the scalp with miniaturization of hairs in the involved area and a decrease in anagen hairs. The patient had extremely low levels of circulating androgen, which is unusual for FPHL. The report suggests that hyperandrogenaemia does not necessarily lead to FPHL, and that FPHL can develop in individuals with extremely low levels of circulating androgen.

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community Alfatradiol is a topical 5AR inhibitor that this study shows is effective in stopping hair loss without sides. It can be bought OTC in Europe right now. Thoughts?

11 upvotes 8 years ago

Hair loss treatments, specifically the use of Alfatradiol as an over-the-counter topical 5AR inhibitor that has been shown to be effective in stopping hair loss without side effects. Other treatments discussed include Minoxidil, finasteride and RU58841.

community On a super stack, but still miniaturizationg going strong???

in Update 8 upvotes 1 year ago

User "Number_Worried00" is using a treatment stack for hair loss, including Minoxidil, Finasteride, Dutasteride, Estradiol, Cetirizine, and Pyrilutamide. Another user suggests that if the cause is vitamin deficiency or inflammation, the stack may not be effective.

community Female Pattern Hair Loss - massive shed after many years on Spironolactone/Minoxidil

in Female 10 upvotes 3 years ago

Female experiencing hair loss for 10 years used 50mg Spironolactone and 5% minoxidil with decent results. Recently had massive shedding, but blood tests were fine and still taking original medications.

community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

in Progress Pictures 271 upvotes 1 year ago

The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

community Finasteride 5mg for female pattern hair loss

in Female 7 upvotes 4 years ago

The user's experience of using Finasteride 5mg and Aldactone 50mg to treat Female Pattern Hair Loss, as well as their use of PRP injections for further hair growth.

community Spironolactone VS dutasteride for female pattern hair loss

in Treatment 7 upvotes 2 months ago

Spironolactone is more potent and lowers testosterone and DHT, while dutasteride only impacts DHT. For female hair loss, checking hormones and considering treatments like oral minoxidil, spironolactone, or topical minoxidil is recommended.

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