Female Pattern Hair Loss in a Patient with 17α-Hydroxylase Deficiency
May 2010
in “
Acta dermato-venereologica
”
TLDR Low androgen levels can still cause female pattern hair loss.
This document is a case report of a 20-year-old woman with 17a-hydroxylase deficiency who presented with female pattern hair loss (FPHL). FPHL is characterized by hair loss primarily on the top of the scalp with miniaturization of hairs in the involved area and a decrease in anagen hairs. The patient had extremely low levels of circulating androgen, which is unusual for FPHL. The report suggests that hyperandrogenaemia does not necessarily lead to FPHL, and that FPHL can develop in individuals with extremely low levels of circulating androgen.
