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    Glossary Wnt antagonist

    substance that blocks Wnt signaling, affecting cell growth

    A Wnt antagonist is a substance that inhibits the Wnt signaling pathway, which is crucial for various biological processes including cell growth, development, and hair follicle formation. By blocking this pathway, Wnt antagonists can affect hair growth and are being studied for their potential in treating conditions like alopecia.

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    Research 30 of 1000+

    1. Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia Molecular and Cellular Endocrinology · 2016 · 47 citations
    2. 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance Journal of Investigative Dermatology · 2016
    3. The GPR30 agonist G-1 promotes hair growth via Wnt/Hedgehog signaling in mice Frontiers in Pharmacology · 2025
    4. 573 Discovery of JW0061, a novel GFRA1 agonist, as a hair regeneration stimulant via WNT signaling activation in dermal papilla cells Journal of Investigative Dermatology · 2024
    5. THE ROLE OF AGONISTS AND ANTAGONISTS OF THE WNT SIGNALING PATHWAY IN PATIENTS WITH ANDROGENIC ALOPECIA AND ALOPECIA AREATA Медико-фармацевтический журнал "Пульс" · 2021
    6. Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice Clinical, Cosmetic and Investigational Dermatology · 2022 · 1 citations
    7. Treatment of Alopecia Areata in Mice by Stimulating the Hair Follicles Using Parathyroid Hormone Agonists Linked to a Collagen Binding Domain Journal of clinical & experimental dermatology research · 2015
    8. 1333 Spheroids cell cultures as a promising study model for hair follice regeneration Journal of Investigative Dermatology · 2018
    9. CCN2 modulates hair follicle cycling in mice Molecular Biology of the Cell · 2013 · 21 citations
    10. New Treatments for Hair Loss Actas Dermo-Sifiliográficas · 2017 · 7 citations
    11. Hair Growth Promotion by δ-Opioid Receptor Activation Biomolecules & Therapeutics · 2021 · 1 citations
    12. GPCRs as key regulators in wound healing Frontiers in Cell and Developmental Biology · 2026
    13. Pathogenic Mechanisms and Mechanism‐Directed Therapies for Androgenetic Alopecia: Current Understanding and Future Directions Dermatologic Therapy · 2025
    14. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    15. TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network Advanced Science · 2026
    16. Deciphering the molecular morphology of the human hair cycle: Wnt signalling during the telogen–anagen transformation British Journal of Dermatology · 2019 · 49 citations
    17. ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth 2022
    18. Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells Current Issues in Molecular Biology · 2023
    19. 676 Wnt and SHH interact to determine hair follicle dermal condensate fate Journal of Investigative Dermatology · 2024
    20. Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network Journal of Biological Chemistry · 2013 · 58 citations
    21. Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells Frontiers in Cell and Developmental Biology · 2020 · 8 citations
    22. The Muscarinic Acetylcholine Receptor in Dermal Papilla Cells Regulates Hair Growth International Journal of Molecular Sciences · 2026
    23. Mesenchyme governs hair follicle induction bioRxiv (Cold Spring Harbor Laboratory) · 2023
    24. The muscarinic acetylcholine receptor in dermal papilla cells regulates hair growth 2024
    25. RSPO1, a potent inducer of pancreatic β cell neogenesis Cell Reports Medicine · 2025 · 1 citations
    26. IL-15 Prolongs Anagen, Stimulates Proliferation, and Suppresses Apoptosis in the Hair Matrix of Human Scalp Hair Follicles Journal of Investigative Dermatology · 2023 · 9 citations
    27. Parathyroid hormone-related peptide and the hair cycle - is it the agonists or the antagonists that cause hair growth? Experimental Dermatology · 2014 · 9 citations
    28. Targeting the Wnt pathways for therapies Molecular and cellular therapies · 2014 · 112 citations
    29. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia Archives of Dermatological Research · 2018 · 39 citations
    30. Undariopsis peterseniana Promotes Hair Growth by the Activation of Wnt/β-Catenin and ERK Pathways Marine Drugs · 2017 · 27 citations