Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This case report documents a female toddler with novel compound heterozygous mutations in the VDR gene causing hereditary 1,25-dihydroxyvitamin D-resistant rickets, expanding the known mutation spectrum for this disease.

This study found that mice lacking the vitamin D receptor (VDR) developed skin tumors more rapidly than those with normal VDR activity, regardless of 1,25-dihydroxyvitamin D(3) presence.

This study found that treatment with mesenchymal stem cell extracellular vesicles enhanced hair growth in mice and stimulated dermal papilla cell activity and growth factor production in vitro.

This study found that both allogeneic and xenogeneic small extracellular vesicles from adipose tissue similarly enhanced soft tissue regeneration and wound healing in rat models, implying similar therapeutic effects across species.

VYC-12L effectively improves skin smoothness, reduces fine lines, and boosts hydration.

This study found that arginine vasotocin is evolutionarily conserved across diverse taxa and may play roles in neuroendocrine, immune, and stress signaling, with potential antimicrobial applications.

This article reviews the use of dermatoscopy and videodermatoscopy in therapeutic follow-up, noting that videodermatoscopy is a reliable tool despite potential cost issues with high magnifications.

This article explains the preparation methods and applications for various vesicle and particle systems used in transdermal drug delivery, highlighting their effectiveness and potential for further development in this field.

This review highlights the crucial role of vitamin D signaling in epidermal stem cells during skin wound healing, emphasizing its distinct functions from calcium metabolism and its importance in genomic regulation mediated by the vitamin D receptor.

This study found that the vitamin D receptor plays a crucial role in hair follicle development in cashmere goats by regulating signaling pathways in dermal papilla cells.

In this study, prenatal ultrasonography was found to be a valuable tool for screening ectodermal dysplasia during pregnancy, and a new EDA gene variant associated with X-linked hypohidrotic ectodermal dysplasia was identified, aiding in more accurate diagnoses and reproductive decision-making.

This study found that the implementation of the SAVe teledermatology model increased access to dermatologic care during COVID-19, reducing referral wait times significantly compared to in-person visits.

This case report details a severe instance of VDR-II where intravenous calcium infusions, administered nightly, successfully improved clinical, radiological, and biochemical signs of rickets without alopecia despite ineffective calcitriol therapy.

This study revealed that Vav2 and Vav3 play roles in regulating hair follicle bulge stem cells in normal conditions and cancer stem cell activation and remodeling in mice.

This review discusses the potential of cell-derived nanovesicles as innovative treatment strategies for hair growth and provides no new clinical results; the authors emphasize the need for further understanding of their mechanisms.

This study found that the PVP protocol, combining Peptichemio, vincristine, and 6-methylprednisolone, resulted in remission for diffuse non-Hodgkin's lymphomas with moderate side effects.

This study re-examined the structure of lanceolate endings in rat vibrissae, suggesting that their apical cones may function as a transducer site for detecting hair movements.

This study evaluated the safety and efficacy of Bio-Pulsed avian mesenchymal stem cell-derived small extracellular vesicles when applied topically, finding significant improvements in hair growth, skin rejuvenation, and regenerative microRNA presence among 60 human participants without adverse events.

This study suggests that 1,25-dihydroxyvitamin D(3) and fibroblast growth factor 23 form a crucial axis in regulating phosphate balance, akin to its role in calcium regulation, and explores novel VDR interactions including with curcumin.

In this study, VVF was found to be a highly variable and unreliable measure of void space in granular scaffolds, sensitive to various input parameters and less predictive than particle count.

This study discovered a novel interaction between the vitamin D receptor and LEF1, essential for normal Wnt signaling in keratinocytes, which is crucial for regular hair cycling.

This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.

This study indicates that while EV-based therapies are advancing towards clinical use in regenerative medicine, addressing methodological and regulatory hurdles is essential to fully harness their therapeutic potential.

This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.

This review explores current strategies to enhance extracellular vesicle-based delivery of CRISPR/Cas systems, addressing efficiency challenges and suggesting future directions to bridge gene editing technologies with clinical applications.

This case report observed that treatment with human placental mesenchymal stromal cell-derived exosome-enriched extracellular vesicles may improve symptoms of chronic cutaneous graft-versus-host disease, including hyperpigmentation and skin ulcers, in a patient resistant to conventional therapies.

This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.

This study found that human mesenchymal stem cell-derived extracellular vesicles promote the proliferation and migration of hair follicle cells and increase hair shaft elongation in cultured human hair follicles.

This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.

This study reports that high-purity rHFSCs with strong proliferation and high VEGF165 expression can be efficiently obtained, facilitating tissue engineering applications like artificial hair follicles and skin construction.