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In mouse studies, this research found that combining ginsenoside Rg3 and glycyrrhizic acid with minoxidil improved treatment outcomes for androgen alopecia by addressing both symptoms and root causes, notably activating the Wnt/β-catenin pathway and promoting hair follicle cell proliferation.

This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.

This study developed and tested Bicalutamide-loaded lipid vesicles in dissolving microarray patches for topical application, finding that they effectively deliver Bicalutamide through murine skin while maintaining a favorable safety profile, suggesting potential to improve treatments for androgenetic alopecia.

This review indicates that various laser therapies, alone or combined with other treatments, show potential in improving hair density and treating androgenetic alopecia, but outcomes can vary, underscoring the importance of personalized treatment.

In this study, a metformin-loaded rosemary-based nanoemulgel was found to significantly enhance hair follicle growth in rats, suggesting its potential as a new treatment for androgenetic alopecia due to its promising physicochemical properties and controlled drug release.

This study developed caffeine-loaded nanoparticles coated with ultradeformable liposomes for better hair follicle delivery, showing non-cytotoxicity and potential to reduce oxidative stress in DHT-damaged cells, suggesting an alternative treatment for androgenetic alopecia.

This study found that Cyanidin-3-O-glucoside and Vitisin A were able to penetrate mouse skin and improve issues related to hair follicle miniaturization and apoptosis in androgenetic alopecia, suggesting these compounds as potential alternative treatments for hair loss.

This review describes ethosomes as promising nanocarriers for delivering active cosmetic ingredients to the skin, potentially transforming treatments for hair loss, acne, and skin pigmentation.

In this study, researchers developed a new topical atraric acid formulation, AA-TF#15, which showed a significantly higher drug penetration and increased hair regrowth in mice compared to minoxidil and finasteride treatments, suggesting its potential effectiveness for treating scalp androgenic alopecia.

This study reviews various treatment options for androgenic alopecia, emphasizing the potential use of drug-loaded nanoparticles, but reports no new research results.

This review discusses the adverse effects of anabolic agents in sports, noting cardiovascular, behavioral, and other side effects, but highlights inconsistencies in the severity of cardiovascular risks.

This review discusses the impact of gender affirming hormone therapy on cardiovascular outcomes in transgender individuals and reports no new clinical results; the authors underscore the need for more comprehensive studies.

This study found that GTx-024 significantly increased total lean body mass and improved physical function in healthy elderly men and postmenopausal women, suggesting potential use for muscle wasting conditions.

In this review, researchers discussed recent advances in nanotechnology for topical skin applications, highlighting how nanocarriers enhance skin penetration and targeting in treatments for diseases like melanoma and psoriasis, while acknowledging that the penetration mechanisms and health impacts of nanoparticles remain not fully understood.

This study found that minoxidil solubilized in gelatin-containing microemulsions resulted in over 5% of the drug remaining in porcine skin, significantly more than the reference gel.

This review discusses the progress in research on topical formulations for treating alopecia, highlighting potential advantages of advanced formulation technologies but reporting no new clinical results.

This article collection reviews the significant influence of gender and sexual hormones on allergies and asthma, noting more severe symptoms in females and the role of estrogen.

This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.

This study found that a lipid-based nanoparticle formulation with oleic acid for delivering dutasteride showed lower skin permeation compared to a formulation without oleic acid, indicating its potential for targeted dermal delivery.

In this study, HA-P5, a nanoparticle derived from peptide and polysaccharide conjugation, effectively reduced acne lesions and sebum production by inhibiting specific receptors in cells, without triggering unfavorable reactions compared to a commercial inhibitor, highlighting HA-P5's potential as a novel acne treatment.

This review highlights significant health risks associated with anabolic-androgenic steroid use in women and reports no new research results, emphasizing the need for further understanding of their effects on female physiology.

This review examines new formulations for delivering 5-α-reductase inhibitors to improve targeted drug delivery in androgenetic alopecia, but reports no new clinical results.

This report discusses a case of localized hypertrichosis that developed after an elderly male with Alzheimer's disease started oral rivastigmine therapy, suggesting a potential link between the drug and hair growth.

This study demonstrated that a finasteride-loaded proniosome significantly enhanced transfollicular delivery and hair growth in mice without causing skin irritation, with effects comparable to a 2% minoxidil solution.

This review reports that clinical studies generally showed favorable results for microneedling as an adjunct therapy for androgenic alopecia and alopecia areata, despite the low quality of existing data.

This review highlights recent developments in nanovesicular carriers for enhancing molecule delivery into and across the skin, focusing on the design and evolution of phospholipid and non-phospholipid systems used in cosmetics and treating various skin conditions.

This narrative review emphasizes the significant improvements in mental well-being linked to gender-affirming treatments while highlighting the need for ongoing research into hormone therapy's long-term effects and its impact on transgender individuals' reproductive health.

This study found that hair care products containing fermented papaya, fermented mangosteen, and caffeine significantly inhibited hair loss, increased hair density and thickness, and improved hair follicle structure in individuals with androgenic or diffuse alopecia over three months compared to placebo and caffeine controls.

This study reported that solid lipid nanoparticles of finasteride decorated with chitosan enhanced drug retention in skin layers, suggesting potential application in treating androgenic alopecia and benign prostate hyperplasia with fewer side effects.