Impacts of Anabolic-Androgenic Steroid Supplementation on Female Health and Offspring: Mechanisms, Side Effects, and Medical Perspectives

The document reviews the impacts of anabolic-androgenic steroid (AAS) supplementation on female health and offspring, highlighting significant health risks such as nervous, cardiac, reproductive, hepatic, and renal system issues. It emphasizes the scarcity of literature on AAS effects in women and the need for systematic investigation. AAS misuse can lead to symptoms like seborrhoea, acne, hirsutism, and androgenic alopecia, with prolonged use causing structural brain changes, psychiatric disorders, hepatotoxicity, renal damage, and oxidative stress. The review notes the lack of sufficient evidence supporting AAS use in women for clinical purposes and calls for more research into their safety and long-term effects, especially given the potential risks to offspring development and the emergence of unregulated steroids on the black market.