Hyperandrogenism, Adrenal Dysfunction, and Hirsutism

    August 2020 in “ Der Hautarzt ”
    Evgenia Makrantonaki, Christos C. Zouboulis
    TLDR Excessive male hormones in women cause symptoms like unwanted hair growth, and treatment requires careful medical evaluation.
    The document discussed conditions of hyperandrogenism and hyperandrogenemia, characterized by excessive androgen levels, leading to symptoms such as hirsutism, seborrhea, acne, and androgenetic alopecia. Hirsutism, or excessive male-pattern hair growth in women, was a key diagnostic criterion. Other symptoms included clitoris hypertrophy, increased muscle mass, irregular menstrual cycles, and metabolic syndrome. Common causes were polycystic ovary syndrome (PCOS), Cushing disease, and late-onset adrenogenital syndrome, with virilization often indicating an androgen-producing tumor. Treatment involved antiandrogens like cyproterone acetate and spironolactone, with a comprehensive clinical evaluation and interdisciplinary approach being crucial for effective diagnosis and treatment.
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