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GlossaryCushing's syndrome (Cushing disease)

condition caused by excessive cortisol, leading to weight gain and skin changes

Cushing's syndrome, also known as hypercortisolism, is a condition characterized by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. This can result from taking corticosteroid medications or from the body producing too much cortisol due to tumors in the pituitary or adrenal glands. Symptoms include weight gain, particularly around the abdomen and face, thinning skin, easy bruising, and in some cases, hair loss or excessive hair growth.

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research Remission in Cushing Disease with Cabergoline

5 citations , May 2008 in “Annals of saudi medicine/Annals of Saudi medicine”

Cabergoline helped a boy with Cushing disease get better after surgery and radiotherapy didn't work.

research Cushing Disease Secondary to Rathke’s Cleft Cyst

October 2025 in “Journal of the Endocrine Society”

Rathke’s cleft cysts can rarely cause Cushing disease, and surgery can improve symptoms.

research Invasive Giant Pituitary Macroadenoma Causing Cushing Disease: A Case Report

April 2021 in “Sri Lanka Journal of Diabetes Endocrinology and Metabolism”

Giant pituitary macroadenomas causing Cushing disease are rare and may need extra treatment if surgery fails.

research A Case Report of Cushing’s Disease Presenting as Hair Loss

6 citations , February 2017 in “Case Reports in Dermatology”

Hair loss led to the diagnosis of Cushing's disease in a patient, showing that hair loss can be a sign of hormonal disorders.

research Skin Signs of Systemic Diseases

21 citations , August 2011 in “Clinics in Dermatology”

Looking at skin can help find and treat serious diseases early.

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community 14 year old struggling with hair loss

in Treatment 8 upvotes 4 years ago

A 14-year-old is experiencing significant hair loss and was prescribed Aminexil by a dermatologist. They are concerned about potential side effects.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 2 years ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community Low cortisol it is due the fin

in Finasteride/Dutasteride 7 upvotes 4 months ago

The user has been taking 1mg finasteride daily for a year with no improvement in hair loss and reports low cortisol levels, sleep issues, and anxiety changes. The conversation includes discussions on the potential effects of finasteride on cortisol and neurosteroids, with suggestions to consult a doctor and consider other factors.

community Almost two months on topical Fin/min

in Is this regrowth? 47 upvotes 8 months ago

A 35-year-old man has been using a topical solution with finasteride, minoxidil, retinoic acid, and hydrocortisone for hair regrowth, experiencing minor side effects. He plans to remove hydrocortisone due to potential long-term health risks.

community Is finasteride losing it effectiveness

in Progress Pictures 75 upvotes 2 years ago

A user experiencing hair loss despite using finasteride, minoxidil, and tretinoin. They're considering trying dutasteride or shaving their head if the situation doesn't improve.

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