Remission in Cushing Disease with Cabergoline

    Raju A. Gopal, Tushar Bandgar, P. S. N. Menon, Nalini Shah
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    Studysummary This case report from India observed that short-term cabergoline treatment brought clinical and biochemical remission in a 12-year-old with persistent Cushing disease after surgery and radiotherapy.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    A 12-year-old boy with persistent Cushing disease (CD) after transsphenoidal surgery (TSS) and radiotherapy (RT) achieved marked clinical and biochemical remission with short-term cabergoline treatment. Despite initial treatments, the patient continued to exhibit symptoms of CD, but after 3 months on cabergoline, significant improvements were observed, including weight loss and decreased cortisol levels. However, discontinuation of cabergoline led to a recurrence of CD, suggesting the remission was due to the drug rather than RT. This case highlighted cabergoline as a potentially effective option for inducing remission in uncured CD patients post-TSS and RT.
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