Remission in Cushing Disease with Cabergoline

    May 2008 in “ Annals of saudi medicine/Annals of Saudi medicine ”
    Raju A. Gopal, Tushar Bandgar, P. S. N. Menon, Nalini Shah
    TLDR Cabergoline helped a boy with Cushing disease get better after surgery and radiotherapy didn't work.
    A 12-year-old boy with persistent Cushing disease (CD) after transsphenoidal surgery (TSS) and radiotherapy (RT) achieved marked clinical and biochemical remission with short-term cabergoline treatment. Despite initial treatments, the patient continued to exhibit symptoms of CD, but after 3 months on cabergoline, significant improvements were observed, including weight loss and decreased cortisol levels. However, discontinuation of cabergoline led to a recurrence of CD, suggesting the remission was due to the drug rather than RT. This case highlighted cabergoline as a potentially effective option for inducing remission in uncured CD patients post-TSS and RT.
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