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    GlossaryCongenital Adrenal Hyperplasia

    genetic disorder causing adrenal gland hormone imbalances

    Congenital Adrenal Hyperplasia (CAH) is a group of genetic disorders affecting the adrenal glands, which are responsible for producing hormones like cortisol and aldosterone. In CAH, enzyme deficiencies lead to an overproduction of androgens (male sex hormones), causing symptoms such as ambiguous genitalia in newborns, early puberty, and excessive hair growth. Treatment typically involves hormone replacement therapy to balance hormone levels.

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      a synthetic cortisol used for anti-inflammatory effects

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      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 9 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community My personal thoughts on DHT. belive it or not

      in Research/Science 3 weeks ago
      The conversation discusses a personal theory on the role of DHT in stress and reproduction, suggesting it converts testosterone for reproductive traits. The discussion includes skepticism and mentions individual differences in physiology and neurochemistry.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 6 months ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community 11-month update. This time wet hair comparison!

      in Progress Pictures  108 upvotes 1 year ago
      The post discusses an 11-month hair loss treatment journey using dutasteride, minoxidil, nizoral, and 1.5mm derma rolling. The responses inquire about the frequency of derma rolling and express optimism for further progress.