For those that have used anti androgens what is your experience?
    3/25/2024

    From the encyclopedia
    RU58841 →

    a potent but unapproved and potentially problematic topical anti-androgen

    Pyrilutamide →

    highly targeted anti-androgen that might have minimal systemic effects

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 RU58841 (topical) varied varied varied
    💧 Pyrilutamide (topical) 16 months
    💊 Finasteride (oral)
    💧 Minoxidil (topical) 5% once daily
    💊 Minoxidil (oral) 1.25mg twice daily
    💊 Dutasteride (oral)
    💧 Fluridil (topical) 2%
    💧 CB-03-01 (topical) 6 years
    💧 Alfatradiol (topical) a couple weeks
    💊 Saw Palmetto (oral) 1.2g daily
    the tone is mixed with varied results.

    Other terms

    People discussed their experiences with anti-androgens for hair loss, mentioning side effects like chest pains with RU58841 and skepticism due to lack of safety data, while considering Fluridil as a potential addition to treatment. Some users expressed reluctance to use these chemicals.
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      New Therapeutics in the Management of Androgenetic Alopecia

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      March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)”
      This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.
      Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

      research Drug discovery for alopecia: gone today, hair tomorrow

      70 citations , February 2015 in “Expert Opinion on Drug Discovery”
      This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.
      Experimental and Early Investigational Drugs for Androgenetic Alopecia

      research Experimental and early investigational drugs for androgenetic alopecia

      11 citations , July 2017 in “Expert Opinion on Investigational Drugs”
      This review discusses current and emerging therapeutic strategies for androgenetic alopecia, noting limited evidence but suggesting areas such as prostaglandin analogs, PRP, and progenitor cell therapies as promising future directions.