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October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
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January 2018 in “PubMed” Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.
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4 citations,
January 2022 in “Yonsei Medical Journal” Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.
24 citations,
November 2018 in “International Journal of Molecular Sciences” Ethosomes improve drug delivery through the skin but may have side effects like irritation.
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July 2015 in “Molecular immunology” Porcine skin is very similar to human skin, making it a useful model for research.
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November 2019 in “Nanomedicine” Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
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July 2023 in “Pharmaceutics (Basel)” Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
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December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
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January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
152 citations,
April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
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March 2018 in “Biomaterials” Tiny needles with valproic acid can effectively regrow hair.
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May 2012 in “European Journal of Dermatology” Menopause affects hair and skin; more research needed for treatment.
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July 2020 in “Expert Opinion on Biological Therapy” Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.
7 citations,
February 2018 in “International Journal of Pharmaceutics” Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.
March 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” Microneedling combined with platelet-rich plasma therapy is more effective for hair regrowth in androgenic alopecia than microneedling alone, but it's more painful.
48 citations,
January 2017 in “International Journal of Trichology” Microneedling with platelet-rich plasma and minoxidil improves hair growth more than just minoxidil in men with hair loss.
47 citations,
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August 2022 in “Journal of Controlled Release” A new microneedle patch effectively promotes hair growth by increasing blood vessel formation around hair follicles.
1 citations,
July 2022 in “Journal of Drug Delivery Science and Technology” Niosomes and ethosomes can effectively carry the drug spironolactone, potentially improving treatment for hair loss and reducing side effects.
March 2024 in “International Journal of Pharmaceutics” Ginsenoside Rg3 combined with minoxidil was more effective in treating hair loss in mice.
November 2023 in “Materials Today Bio” The new treatment using nanoparticles with ISX9 can effectively regrow hair without major side effects.
April 2023 in “Journal of Drug Delivery Science and Technology” The new minoxidil gel improves hair growth and reduces skin irritation.
12 citations,
May 2013 in “International Journal of Dermatology” Ethosomes improve black tea extract absorption in hair dye.
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