Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study aimed to develop a new transdermal patch for treating androgenetic alopecia using finasteride, combined with chemical permeation enhancers to improve drug delivery through the skin, but results of pharmacokinetics and pharmacodynamics evaluations are not reported.

This study reported that using photoacoustic waves to enhance transdermal delivery of encapsulated minoxidil can significantly increase hair growth while reducing treatment frequency and systemic side effects.

This study observed that chitosan-decorated PS404-b-PAA63 nanoparticles may enhance skin retention and reduce permeation flux of finasteride, suggesting potential for improved transdermal delivery.

This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.

This review discusses the advantages, applications, and current trends of dissolving microneedles for drug delivery across various therapeutic areas and reports no new clinical results.

This paper reviews strategies to enhance the effectiveness of topical drug delivery by addressing skin barrier challenges, optimizing drug delivery systems, and personalizing treatment approaches, highlighting both current advancements and limitations in the field.

This review summarizes recent advances in alopecia management, focusing on combining synthetic and herbal therapies with innovative drug delivery systems like nanocarriers to enhance effectiveness and reduce side effects, while noting challenges with skin penetration and bioavailability.

This review highlights the potential of microneedle technology in traditional Chinese medicine as a promising transdermal delivery system for skin diseases, showcasing improved efficacy and reduced side effects of TCM ingredients while discussing the challenges of its clinical application.

This study reported that an ATRA-loaded nanostructured lipid carrier gel (ATRA-NLC-Gel) improved symptoms of alopecia areata in mice by enhancing transdermal drug delivery, reducing skin irritation, and promoting hair regrowth through targeted follicle enrichment and pathway activation.

This study highlights the potential of chitosan nanoparticles to improve cannabidiol solubility and delivery for treating alopecia, suggesting a promising approach for transdermal delivery of hydrophobic compounds.

This literature review discusses exosomes' potential as biomarkers and therapeutics for skin issues, hair loss, and wound healing, but notes that their full functions and standardized applications remain inadequately understood.

This research observed that oral testosterone replacement therapy significantly increases cardiovascular risk, while effects of injected or transdermal therapy on cardiovascular risk were not significant, prompting further investigation into these methods.

This review discusses the biological properties of 18β‐glycyrrhetinic acid derived from licorice root, highlighting its potential anti-inflammatory, antioxidant, and antimicrobial benefits in treating dermatological disorders, and reports no new experimental results.

This study found that a microneedle array patch using a blend of kangfuxin, chitosan, and fucoidan significantly accelerated wound healing in rats by enhancing epithelial thickness and collagen deposition.

This guideline provides evidence-based recommendations for prescribing testosterone therapy to women with hypoactive sexual desire disorder, noting a moderate therapeutic benefit but highlighting limited data and regulatory challenges.

This review discusses how polymer-based nanocarriers can enhance drug delivery targeting hair follicles for acne treatment, focusing on factors affecting this delivery method, combination technologies to improve follicle targeting, and recent advancements in polymer nanodrug-delivery systems.

This review highlights that while nanoparticle-loaded dissolving microneedles have considerable promise for enhancing transdermal drug delivery, progress is delayed by insufficient understanding of their in vivo behavior, which the authors emphasize as crucial for advancing clinical applications.

In this study, a hydrogel with anti-inflammatory, antibacterial, antioxidant, and wound tissue adhesion properties was developed, showing significant potential for wound healing and suggesting it could offer a new and effective treatment option in clinical settings.

This review highlights recent advancements in microneedle technology, noting its ability to enhance transdermal drug delivery, biosensing, cancer treatment, and skin disease repair, while emphasizing its potential for improving patient compliance and reducing side effects.

This study provides a guideline for the safe and effective use of testosterone in women with hypoactive sexual desire disorder, recommending systemic transdermal testosterone for appropriate candidates while highlighting the importance of informed consent and monitoring due to unestablished long-term safety.

This case report highlights the importance of considering exogenous androgen exposure, such as transdermal testosterone cream used by a partner, in the diagnosis of virilization among women.

This review discusses the biological effects of honokiol for treating skin diseases and reports no new clinical results; the authors recommend further exploration of topical applications.

This study found that diffusion coefficients of chemicals in artificial sebum are significantly higher than those in stratum corneum lipids, suggesting the hair follicle may significantly contribute to transdermal permeation.

This review discusses the role of exosomes in medical aesthetics, focusing on their mechanisms, production, and preservation, but reports no new clinical results and highlights barriers to their widespread application.

In this study, researchers observed that phospholipid-calcium carbonate hybrid nanoparticles effectively delivered Tofacitinib citrate topically, which significantly inhibited hair follicle apoptosis and promoted hair growth in a mouse model of chemotherapy-induced alopecia, compared to a traditional Tofacitinib solution.

This article reviews the role of testosterone in sexual health, supporting Testosterone Replacement Therapy as an effective treatment for Hypoactive Sexual Desire Disorder in postmenopausal women, though more research is needed on its long-term effects and applicability to premenopausal women.

This review examines the use of microneedles for treating alopecia areata, highlighting their ability to enhance drug delivery through the skin by bypassing the outer barrier and promoting hair growth with minimal invasiveness.

This chapter reviews ethosomes for targeted drug delivery to the scalp in androgenetic alopecia and reports no clinical results; the authors emphasize reducing systemic side effects.

This study found that using a stevioside-based microneedle patch significantly increased minoxidil's solubility and skin absorption, promoting hair growth in animal models and achieving 67.5% area coverage by day 35, highlighting the potential of this novel delivery system for androgenetic alopecia treatment.

This review discusses metal-organic frameworks for treating diabetic infected wounds and related applications, reporting no new clinical results but highlighting challenges like biosafety and production for future research.