International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women

April 2021 in “ Climacteric ”

Sharon J. Parish, James A. Simon, Susan R. Davis, Annamaria Giraldi, Irwin Goldstein, S. Goldstein, Noel N. Kim, Sheryl A. Kingsberg, Abraham Morgentaler, Rossella E. Nappi, Kwangsung Park, Cynthia A. Stuenkel, Abdulmaged M. Traish, Linda Vignozzi

systemic testosterone hypoactive sexual desire disorder transdermal testosterone therapy androgenic side effects biopsychosocial approach pharmacologic options non-pharmacologic options

Studysummary This study provides a guideline for the safe and effective use of testosterone in women with hypoactive sexual desire disorder, recommending systemic transdermal testosterone for appropriate candidates while highlighting the importance of informed consent and monitoring due to unestablished long-term safety.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on tandfonline.com →

Discuss this study in the Community →

Research cited in this study

9 / 9 results

research Sexuality in Premature Ovarian Insufficiency

32 citations , March 2019 in “Climacteric”

This review examines the impact of spontaneous premature ovarian insufficiency on women's sexual function and highlights the need for a comprehensive, biopsychosocial approach to management, but presents no new clinical results.

research Androgens and Female Sexual Function and Dysfunction—Findings From the Fourth International Consultation of Sexual Medicine

75 citations , February 2016 in “The Journal of Sexual Medicine”

This review highlights the efficacy of transdermal testosterone therapy in improving sexual function in women with hypoactive sexual desire disorder, though approved formulations and long-term safety data are limited.

research On the Effects of Testosterone on Brain Behavioral Functions

186 citations , February 2015 in “Frontiers in Neuroscience”

This review discusses the complex effects of testosterone on the brain, emphasizing sex differences, and reports no clinical results; the authors highlight the inconsistencies in current study findings.

research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline

251 citations , October 2014 in “The Journal of Clinical Endocrinology & Metabolism”

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

research Pharmacokinetics of a Transdermal Testosterone Cream in Healthy Postmenopausal Women

18 citations , May 2014 in “Menopause”

This study found that a 5-mg daily dose of transdermal testosterone cream in postmenopausal women restored testosterone levels to those typical of premenopausal women.

Testosterone Improves Antidepressant-Emergent Loss of Libido in Women: Findings from a Randomized, Double-Blind, Placebo-Controlled Trial

research Testosterone Improves Antidepressant-Emergent Loss of Libido in Women: Findings from a Randomized, Double-Blind, Placebo-Controlled Trial

36 citations , January 2014 in “The Journal of Sexual Medicine”

This study found that transdermal testosterone significantly increased the frequency of satisfactory sexual events in women experiencing SSRI/SNRI-related loss of libido, but did not improve overall sexual self-rating scores.

Summary of the Recommendations on Sexual Dysfunctions in Women