A Finasteride Patch for the Treatment of Androgenetic Alopecia: Study on Permeability Strategy Using Synthetic O-Acylmenthols and Ion-Pair

    October 2024 in “ International Journal of Pharmaceutics ”
    Hui Li, Peng Sun, Shuhan Liu … Liang Fang
    Studysummary This study aimed to develop a new transdermal patch for treating androgenetic alopecia using finasteride, combined with chemical permeation enhancers to improve drug delivery through the skin, but results of pharmacokinetics and pharmacodynamics evaluations are not reported.
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    Research cited in this study 11

    1. Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management Journal of Drug Delivery Science and Technology · 2023
    2. Androgenetic Alopecia: Therapy Update Drugs · 2023
    3. Natural Products for Male Androgenetic Alopecia Dermatologic Therapy · 2022
    4. Novel Tip-Loaded Dissolving and Implantable Microneedle Array Patches for Sustained Release of Finasteride International Journal of Pharmaceutics · 2021
    5. Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target Journal of Medicinal Chemistry · 2021
    6. Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers Pharmaceutical Research · 2020
    7. Androgenetic Alopecia: Effects of Oral Finasteride on Hormone Profile, Reproduction, and Sexual Function Endocrine · 2020
    8. Development of Finasteride Polymer Microspheres for Systemic Application in Androgenic Alopecia International Journal of Molecular Medicine · 2019
    9. Preformulation Studies of Finasteride to Design Matrix Systems for Topical Delivery Journal of Pharmaceutical and Biomedical Analysis · 2018
    10. Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice BMC Complementary and Alternative Medicine · 2017
    11. Structural Characterization of Polymorphs and Molecular Complexes of Finasteride Journal of Molecular Structure · 1999

    Related research 1

    1. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003