Preformulation Studies of Finasteride to Design Matrix Systems for Topical Delivery

    August 2018 in “ Journal of Pharmaceutical and Biomedical Analysis ”
    Stephania G.B. Lima, Ludmila A.G. Pinho, Maíra N. Pereira … Angel Concheiro
    Studysummary This study found that finasteride maintained chemical and physical stability in various excipient mixtures, which may guide the development of stable topical delivery systems.
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    Research cited in this study 9

    1. Experimental, Molecular Docking Investigations and Bioavailability Study on the Inclusion Complexes of Finasteride and Cyclodextrins Drug Design Development and Therapy · 2017
    2. Effects of a Novel Finasteride 0.25% Topical Solution on Scalp and Serum Dihydrotestosterone in Healthy Men with Androgenetic Alopecia International Journal of Clinical Pharmacology and Therapeutics · 2015
    3. Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms: Does Form X Exist? Journal of Pharmaceutical Sciences · 2015
    4. Quality Evaluation of the Finasteride Polymorphic Forms I and II in Capsules Journal of Pharmaceutical and Biomedical Analysis · 2014
    5. Topical Formulations Containing Finasteride: In Vitro Permeation/Penetration Study and In Vivo Pharmacokinetics in Hairless Rat Journal of Pharmaceutical Sciences · 2014
    6. Design and In Vitro Evaluation of Finasteride-Loaded Liquid Crystalline Nanoparticles for Topical Delivery Aaps Pharmscitech · 2012
    7. Physicochemical Characterization of Finasteride: PEG 6000 and Finasteride: Kollidon K25 Solid Dispersions, and Finasteride: Beta-Cyclodextrin Inclusion Complexes Journal of Inclusion Phenomena and Macrocyclic Chemistry · 2010
    8. Structural Study of Polymorphs and Solvates of Finasteride Journal of Pharmaceutical Sciences · 2007
    9. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006