Physicochemical Characterization of Finasteride: PEG 6000 and Finasteride: Kollidon K25 Solid Dispersions, and Finasteride: Beta-Cyclodextrin Inclusion Complexes

    August 2011 in “ Journal of Inclusion Phenomena and Macrocyclic Chemistry ”
    Hugo F. D. Almeida, Helena Marques
    Image of study
    TLDR Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.
    This study investigated the formation of solid dispersions and inclusion complexes of finasteride to improve its solubility and bioavailability. The results showed that solid dispersions with PEG 6000 and Kollidon K25, and inclusion complexes with β-cyclodextrin, increased finasteride dissolution rate. The DSC thermograms revealed the transformation of finasteride into the amorphous state in these formulations, and the IR spectra demonstrated molecular interaction.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Making topical finasteride solution

      in Finasteride/Dutasteride  1 upvotes 8 months ago
      The user has been mixing finasteride with stemoxydine for hair loss and is considering switching to a less expensive product with a different ingredient list. They are questioning if the new product's higher water content compared to alcohol will affect the finasteride's solubility.

      community How to make topical finasteride?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The conversation is about making a topical finasteride solution by dissolving crushed finasteride tablets in an alcohol-based hair treatment. Ingredients of the hair treatment include alcohol, water, and various plant extracts and preservatives.

      community Discussion on Finasteride and life.

      in Chat  162 upvotes 1 month ago
      Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

      community Carrier for homemade topical Finasteride

      in Chat  6 upvotes 6 months ago
      The conversation is about making topical finasteride using stemoxydine as a carrier. The user is considering buying Redken Cerafill Hair Re-Densifying Treatment (Stemoxydine) 90ml for this purpose.

    Similar Research

    5 / 1000+ results