TLDR Created finasteride complex to increase water solubility and drug release.
The study developed a crystalline inclusion complex (CIC) of finasteride using electrospraying as a novel approach to improve its water solubility. The optimized parameters for preparing the CIC were an operating voltage of 18 kV, flow rate of 1.0 mL/h, and tip to collector distance of 15 cm. The CIC was characterized using various techniques, and the results showed that the process did not change the solid state of the drug. The in vitro release study showed a 1.6-fold increase in drug release compared to the unprocessed drug. The developed formulation was stable for 3 months at 25 °C.
28 citations,
February 2016 in “International Journal of Nanomedicine” Finasteride capsules with nanoparticles improve drug delivery, solubility, stability, and effectiveness.
47 citations,
February 2014 in “Aaps Pharmscitech” Improved hair loss treatment using special particles and surfactants.
4 citations,
January 2013 in “Dissolution Technologies” A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.
11 citations,
August 2011 in “Journal of Inclusion Phenomena and Macrocyclic Chemistry” Finasteride's solubility and bioavailability improved by forming solid dispersions and inclusion complexes.
61 citations,
May 2007 in “Journal of Pharmaceutical Sciences” Different forms of hair loss drug can improve effectiveness.
November 2020 in “Journal of The American Academy of Dermatology” Finasteride 1 mg every other month works as well as daily dose for hair loss maintenance.
January 2013 in “e-Jurnal Medika Udayana” 
12 citations,
August 2004 in “PubMed” Finasteride, especially in a 1mg dose, effectively slows hair loss and improves hair growth in Japanese men with male pattern hair loss.
38 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
10 citations,
June 2001 in “PubMed” Finasteride is effective in growing hair and stopping hair loss in men with mild to moderate alopecia.
3 citations,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
