TLDR Created finasteride complex to increase water solubility and drug release.
The study developed a crystalline inclusion complex (CIC) of finasteride using electrospraying as a novel approach to improve its water solubility. The optimized parameters for preparing the CIC were an operating voltage of 18 kV, flow rate of 1.0 mL/h, and tip to collector distance of 15 cm. The CIC was characterized using various techniques, and the results showed that the process did not change the solid state of the drug. The in vitro release study showed a 1.6-fold increase in drug release compared to the unprocessed drug. The developed formulation was stable for 3 months at 25 °C.
Cited in this study
5 / 5 results
28 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
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June 2001 in “PubMed” Finasteride is effective in growing hair and stopping hair loss in men with mild to moderate alopecia.
3 citations
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October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
