Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms: Does Form X Exist?

    February 2015 in “ Journal of Pharmaceutical Sciences
    Jadwiga Frelek, Marcin Górecki, Alicja Dziedzic, Ewa Jabƚońska, Bohdan Kamieński, Ryszard K. Wojcieszczyk, Roman Luboradzki, Wojciech J. Szczepek
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    Studysummary This study found that the polymorphic forms I, II, and III of finasteride can be prepared purely, with form III being identical to what was previously referred to as form X.
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    This document is a scientific study that characterizes the different polymorphic forms of finasteride, a drug used to treat hair loss. The study uses various spectroscopic techniques to identify the different forms of finasteride and their chemical properties. The study concludes that there are three different polymorphic forms of finasteride, and that they differ slightly in their chemical properties. The study also provides information on the conformation of finasteride in its different forms. The study also confirms that the so-called "form X" of finasteride does not exist.
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