Experimental, Molecular Docking Investigations and Bioavailability Study on the Inclusion Complexes of Finasteride and Cyclodextrins

    Fatma M. Mady, Usama Farghaly Aly
    Image of study
    TLDR Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
    This document reports on a study investigating the use of cyclodextrins to improve the solubility and bioavailability of finasteride, a drug used to treat hair loss. The study found that the inclusion complexes of finasteride and cyclodextrins had improved solubility and dissolution rates compared to the raw drug. The study suggests that the use of cyclodextrins could enhance the bioavailability of finasteride. The study involved various analyses, including X-ray diffraction, DSC analysis, molecular docking studies, dissolution rate studies, and pharmacokinetic studies in rabbits.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 1000+ results

      community 18M: Side Effects After 3 Months on Topical Finasteride

      in Finasteride  100 upvotes 2 days ago
      An 18-year-old using topical finasteride for hair loss is experiencing side effects like delayed ejaculation and lower sex drive after three months. They are considering whether to continue with the treatment or adjust it, possibly switching back to minoxidil.

      community When should I start using Finasteride (21M)

      in Finasteride  68 upvotes 1 week ago
      A 21-year-old male recently had a hair transplant and is considering starting finasteride to prevent further hair loss. Finasteride can be started immediately to maintain existing hair, with potential side effects like decreased libido, and results may take several months.

      community Where to get finasteride with no insurance?

      in Finasteride  31 upvotes 3 weeks ago
      Finasteride can be purchased at competitive prices from Costco, Amazon, and Cost Plus Drugs, with GoodRx offering local deals. Splitting 5mg tablets may reduce costs if approved by a doctor.

      community Is Topical Finasteride Safe for Cats in My Home?

      in Finasteride  46 upvotes 1 month ago
      Topical finasteride is not known to be toxic to cats like minoxidil, but careful handling is advised to prevent ingestion or skin contact. OP seeks reassurance to convince their girlfriend of its safety around their cat.

    Similar Research

    5 / 1000+ results