A Rapid, Simple, Liquid Chromatographic-Electrospray Ionization, Ion Trap Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study

    January 2012 in “ PubMed ”
    Syed Husain Hashemi Mousavi, Farzad Kobarfard, Syed Akhtar Husain … Amir Mehdizadeh
    Studysummary This study developed and validated a reliable method using chromatography and mass spectrometry to accurately measure finasteride levels in human plasma.
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    Research cited in this study 11

    1. Bioequivalence Study of Finasteride Drug Research · 2011
    2. A Rapid, Simple, Specific Liquid Chromatographic–Electrospray Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study Journal of Pharmaceutical and Biomedical Analysis · 2006
    3. Polarographic Behavior and Determination of Finasteride Farmaco · 2003
    4. Separation of Finasteride and Analogues Journal of Chromatography B: Biomedical Sciences and Applications · 2001
    5. LC Determination of Finasteride and Its Application to Storage Stability Studies Journal of Pharmaceutical and Biomedical Analysis · 2001
    6. Determination of Finasteride in Human Plasma by Liquid-Liquid Extraction and High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 2000
    7. Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations Analytical Chemistry · 1998
    8. Finasteride in Biological Fluids: Extraction and Separation by a Graphitized Carbon Black Cartridge and Quantification by High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 1997
    9. High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching Journal of Chromatography B: Biomedical Sciences and Applications · 1996
    10. Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method Journal of Chromatography B: Biomedical Sciences and Applications · 1995
    11. Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry Journal of Chromatography B: Biomedical Sciences and Applications · 1994

    Related research 3

    1. A Rapid, Simple, Specific Liquid Chromatographic–Electrospray Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study Journal of Pharmaceutical and Biomedical Analysis · 2006
    2. Determination of Finasteride in Human Plasma by HPLC-MS Chinese Journal of Hospital Pharmacy · 2005
    3. HPLC-APCI-MS Determination of Finasteride in Human Plasma Yaowu fenxi zazhi · 2005