Bioequivalence Study of Finasteride

December 2011 in “ Drug Research ”

Fabiana Gatti de Menezes, Wellington Souto Ribeiro, Demian R. Ifa, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes, Gilberto De Nucci

finasteride bioequivalence hair loss benign prostatic hyperplasia hepatic metabolism biliary excretion Propecia

TLDR Finasteride's two formulations absorb similarly, showing bioequivalence.

This document is a bioequivalence study of finasteride, a drug used to treat hair loss and benign prostatic hyperplasia. The study found that there were no significant differences in the rate and extent of absorption between two different formulations of finasteride, indicating bioequivalence. The method used to analyze the drug in human plasma was found to be accurate and suitable for routine analysis. The study also noted the role of hepatic metabolism and biliary excretion in the disposition of the drug.

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community Out of curiosity, why are Finasteride pills formulated as small tablets, while Dutasteride pills are much larger soft gel capsules?

in Finasteride/Dutasteride 41 upvotes 11 months ago

Finasteride and Dutasteride are used for hair loss, with Dutasteride often in gel form for better bioavailability. Switching from Finasteride to Dutasteride is common, with some users combining treatments like Minoxidil for improved results.

community Reminder: you can get dutasteride for $6.33 / month in the United States

in Finasteride/Dutasteride 67 upvotes 1 year ago

Dutasteride can be obtained for $6.33 per month in the US through Cost Plus Drugs, with prescriptions easily switched from finasteride by contacting a doctor. Users discuss various methods to obtain affordable dutasteride, including using online pharmacies and considering generic options, while cautioning against buying from unreliable sources like eBay.

community Experiencing Anxiety and Fatigue After 1 Week on Finasteride – Looking for Advice

in Finasteride 74 upvotes 1 day ago

The user experienced anxiety, dizziness, and fatigue after starting finasteride and is seeking advice on whether to continue, adjust the dose, or consult a doctor. They stopped taking finasteride and are unsure if it caused their symptoms.

community 18M, 8 Months on Minoxidil & Finasteride, Considering Dermaroller for Hairline Regrowth

in Finasteride 61 upvotes 1 week ago

The user is experiencing hair loss at Norwood 2.5 and is using minoxidil, finasteride, and vitamins, noticing minimal regrowth after 8 months. They are considering using a dermaroller but are unsure of its effectiveness.

community Concern About Misapplication of Finasteride/Minoxidil After 2 Years Use and Hairline Recession

in Finasteride 98 upvotes 1 week ago

The user experienced hairline recession despite using topical finasteride/minoxidil and is considering whether misapplication was the cause. They are exploring options after experiencing side effects from oral finasteride, including possibly returning to the topical formulation with adjusted application methods.

community 18M Using Finasteride and Minoxidil: No Improvement in Hair Density Since February

in Finasteride 50 upvotes 2 weeks ago

An 18-year-old using finasteride since February and minoxidil since July has not seen improvement in hair density. They are advised to continue treatment as results can take up to a year, and to consider other options if no change occurs after a full year.

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