Bioequivalence Study of Finasteride

    December 2011 in “ Drug Research ”
    Fabiana Gatti de Menezes, Wellington Souto Ribeiro, Demian R. Ifa, Maria Elisabete Amaral de Moraes, Manoel Odorico de Moraes, Gilberto De Nucci
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    TLDR Finasteride's two formulations absorb similarly, showing bioequivalence.
    This document is a bioequivalence study of finasteride, a drug used to treat hair loss and benign prostatic hyperplasia. The study found that there were no significant differences in the rate and extent of absorption between two different formulations of finasteride, indicating bioequivalence. The method used to analyze the drug in human plasma was found to be accurate and suitable for routine analysis. The study also noted the role of hepatic metabolism and biliary excretion in the disposition of the drug.
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