Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers

May 2020 in “ Pharmaceutical Research ”

H.A. Farah, Matthew A. Brown, William J. McAuley

finasteride heat chemical penetration enhancers human scalp skin hair follicles androgenetic alopecia topical finasteride Propecia

TLDR Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.

The study investigated the use of heat and chemical penetration enhancers to improve the delivery of finasteride to human scalp skin and hair follicles. The results showed that short durations of externally applied heat significantly increased finasteride penetration into human scalp skin after 24 hours. The use of short durations of heat in combination with specific chemical penetration enhancers was able to increase the delivery of finasteride to human scalp skin and provide focused drug delivery to the hair follicles. The study suggests that this approach could be used to enhance the efficacy of topical finasteride for the treatment of androgenetic alopecia.

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11 / 11 results

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2 / 2 results

research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers

5 citations , May 2020 in “Pharmaceutical Research”

Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.

research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

82 citations , January 2002 in “Journal of drug targeting”

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.