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5 / 1000+ resultsresearch Ion Pairs of Risedronate for Transdermal Delivery and Enhanced Permeation Rate on Hairless Mouse Skin
Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
research Rapid Determination of Minoxidil in Human Plasma Using Ion-Pair HPLC
Quick method to measure minoxidil in blood, accurate and useful for labs.
research A Finasteride Patch for the Treatment of Androgenetic Alopecia: Study on Permeability Strategy Using Synthetic O-Acylmenthols and Ion-Pair
This study explores the development of a finasteride (FIN) transdermal patch for treating androgenetic alopecia (AGA) using ion-pair and O-acylmenthols (AM) as chemical permeation enhancers (CPEs). The patch formulation was optimized through single-factor investigation and Box-Behnken design, and its pharmacokinetics and pharmacodynamics were evaluated. The study examined the permeability enhancement mechanisms of ion-pair and AMs at both the patch and skin levels using various analytical techniques. The optimized FIN patch formulation includes 5% synthetic FIN-CA, 6% MT-C6 as CPEs, and 25-AAOH as a pressure-sensitive adhesive, with a thickness of 80 ± 5 μm.
research PH Dependence of the Coiled-Coil Structure of Keratin Intermediate Filament in Human Hair by 13C NMR Spectroscopy and the Mechanism of Its Disruption
Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.
research Recent Studies on the Delivery of Hydrophilic Drugs in Nanoparticulate Systems
Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
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5 / 22 resultscommunity hairline resurrection — 2 months before/after [5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, weekly 0.5mm dermarolling]
This conversation was about a user named Substantial_Pen_1099 who has been using an regimen of 5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, and weekly 0.5mm dermarolling for hair loss treatment over the course of 3 months. Others in the conversation expressed disbelief at their progress, to which Substantial_Pen_1099 provided video proof as evidence.
community 3.5 months on 7%Minoxdil - 0.1%Finasteride - .025%Tret (Topical)
The user noticed a significant improvement in hair loss after 3.5 months using a topical treatment of 7% Minoxidil, 0.1% Finasteride, and 0.025% Tretinoin, which was prescribed and shipped from a pharmacy in Indiana. Other users discussed alternative products with varying concentrations of Minoxidil and Finasteride.
community Electrical devices like violet ray for hair regrowth
The conversation discusses using a violet ray device for hair regrowth, citing a case where zinc ion treatments showed promising results. It also mentions similar devices like the Growcombr and niostem helmet.
community Black dots coming in along hairline, sign of regrowth?
User noticed black dots along the hairline and temples, questioning if it's regrowth. They are using a regimen including Dutasteride, oral and topical Minoxidil, and a compounded topical treatment.
community Maybe oral min was not that good of an idea for someone this naturally hairy
User discusses increased body hair after using oral minoxidil for hair loss treatment. Others share experiences and debate benefits of being hairy versus bald.