Interdisciplinary Traditional Chinese Medicine Microneedles in Skin Disease Treatment: Recent Advances and Challenges

    October 2025 in “ Bioactive Materials ”
    Xinyue Cao, Rong He, Dongyu Xu, Yuanjin Zhao
    Studysummary This review highlights the potential of microneedle technology in traditional Chinese medicine as a promising transdermal delivery system for skin diseases, showcasing improved efficacy and reduced side effects of TCM ingredients while discussing the challenges of its clinical application.
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    Research cited in this study 21

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    3. Hyaluronic Acid Microneedles Loaded With Chinese Herbal Extracts as an Intradermal Delivery System for Hair Regeneration Biomacromolecules · 2025
    4. Tremella Polysaccharide Microneedles Loaded With Magnetic Dental Pulp Stem Cell Intracellular Vesicles Used For Androgenic Alopecia Stem Cell Research & Therapy · 2025
    5. Microneedle-Mediated Hypoxic Extracellular Vesicle-Encapsulated Selenium Nanoparticles Delivery to Treat Androgenetic Alopecia Journal of Controlled Release · 2025
    6. Gas-Propelled Anti-Hair Follicle Aging Microneedle Patch for the Treatment of Androgenetic Alopecia Journal of Controlled Release · 2025
    7. Clinical, Biochemical, and Molecular Characteristics of Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Journal of Clinical Research in Pediatric Endocrinology · 2024
    8. Synergistic Therapeutic Effect of Ginsenoside Rg3 Modified Minoxidil Transfersomes on Androgenic Alopecia in C57BL/6 Mice International Journal of Pharmaceutics · 2024
    9. Dissolvable Microneedles Loaded with Ginsenoside Rg3 Liposome: A Transdermal Delivery Approach for Alopecia Treatment Regenerative Biomaterials · 2024
    10. Long-Acting Microneedle Formulations Advanced Drug Delivery Reviews · 2023
    11. Going Below and Beyond the Surface: Microneedle Structure, Materials, Drugs, Fabrication, and Applications for Wound Healing and Tissue Regeneration Bioactive Materials · 2023
    12. Dissolving Microneedle Patch Integrated With Microspheres For Long-Acting Hair Regrowth Therapy ACS Applied Materials & Interfaces · 2023
    13. Composite Double-Layer Microneedle Loaded With Traditional Chinese Medicine for the Treatment of Androgenic Alopecia Medicine in novel technology and devices · 2023
    14. Curcumin-Zinc Framework Encapsulated Microneedle Patch for Promoting Hair Growth Theranostics · 2023
    15. A Combination Therapy for Androgenic Alopecia Based on Quercetin and Zinc/Copper Dual-Doped Mesoporous Silica Nanocomposite Microneedle Patch Bioactive Materials · 2022
    16. Traditional Chinese Medicine Treatment for Androgenetic Alopecia Based on Animal Experiments: A Systematic Review and Meta-Analysis Evidence-based Complementary and Alternative Medicine · 2022
    17. Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases Frontiers in medicine · 2022
    18. Dissolving Microneedles: Applications and Growing Therapeutic Potential Journal of Controlled Release · 2022
    19. Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment Theranostics · 2022
    20. Recent Understandings of Biology, Prophylaxis, and Treatment Strategies for Hypertrophic Scars and Keloids International journal of molecular sciences · 2018
    21. Air Pollution and Skin Diseases: Adverse Effects of Airborne Particulate Matter on Various Skin Conditions Life Sciences · 2016