Traditional Chinese Medicine Treatment for Androgenetic Alopecia Based on Animal Experiments: A Systematic Review and Meta-Analysis

    Yanbo Liang, Jing Yuan, Nururshopa Eskander Shazada, Jun Jiang, Jianlin Wu
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    Studysummary This study found that Traditional Chinese Medicine increased hair follicle numbers and improved hair growth metrics in androgenetic alopecia rodent models, suggesting potential benefits linked to reduced serum testosterone levels. Our plain-language summary of this paper — not a Tressless recommendation.
    This systematic review and meta-analysis evaluated the effects of Traditional Chinese Medicine (TCM) on androgenetic alopecia (AGA) in rodent models, including 15 studies. TCM treatment increased the total number of hair follicles and the terminal hair/vellus hair ratio, while reducing skin discoloration time and skin hair growth time. These effects were linked to a reduction in serum testosterone levels, though no significant differences were found in serum estradiol levels or skin tissue hormone levels. The study suggests TCM may be effective for AGA but calls for high-quality studies to confirm these findings.
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