Microneedling for Hair Loss

October 2021 in “ Journal of Cosmetic Dermatology ”

Anik Gupta, Emma M Quinlan, Maanasa Venkataraman, Mary A Bamimore

microneedling androgenetic alopecia minoxidil platelet-rich plasma hair follicle stem cells Wnt/β-catenin signaling pathway follicular sulfotransferase enzymes Rogaine PRP

TLDR Microneedling is an effective and minimally invasive treatment for hair loss.

Microneedling is reviewed as a promising treatment for androgenetic alopecia, showing significant hair regrowth in various studies, especially when combined with treatments like minoxidil and platelet-rich plasma. It works by stimulating hair follicle stem cells and activating the Wnt/β-catenin signaling pathway, and enhances the response to minoxidil by upregulating follicular sulfotransferase enzymes. Overall, microneedling is a minimally invasive and effective option for hair loss.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

16 / 16 results

research Radiofrequency Microneedling: A Comprehensive and Critical Review

28 citations, February 2021 in “Dermatologic Surgery”

Radiofrequency microneedling is an effective and safe treatment for various skin conditions and works well with other treatments and on darker skin.

research Combination Therapy with Topical Minoxidil and Nano-Microneedle-Assisted Fibroblast Growth Factor for Male Androgenetic Alopecia: A Randomized Controlled Trial in Chinese Patients

6 citations, November 2020 in “Chinese Medical Journal”

Combining minoxidil and fibroblast growth factor is more effective for treating male hair loss than using either alone.

research Microneedling in Androgenetic Alopecia: Comparing Two Different Depths of Microneedles

10 citations, September 2020 in “Journal of Cosmetic Dermatology”

Deeper microneedling boosts hair growth, with 0.6mm needles and minoxidil being most effective.

research Usefulness of Home-Use Microneedle Devices in the Treatment of Pattern Hair Loss

11 citations, June 2020 in “Journal of cosmetic dermatology”

Home-use microneedle devices might safely boost 5% minoxidil's effectiveness for hair growth.

Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway

research Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway

10 citations, May 2020 in “Journal of Dermatological Treatment”

Microneedling with 5% minoxidil improves hair loss in Chinese men by activating Wnt/ß-catenin pathway.

Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia in Men and Women: A Systematic Review with Network Meta-Analyses and an Assessment of Evidence Quality

15 citations, April 2020 in “Journal of Dermatological Treatment”

Minoxidil and finasteride work best for hair loss; more research needed.

research Dermoscopic Assessment of Microneedling Alone Versus Microneedling with Platelet-Rich Plasma in Cases of Male Pattern Alopecia: A Split-Head Comparative Study

5 citations, January 2020 in “International Journal of Trichology”

Microneedling alone is as effective as microneedling with platelet-rich plasma for male pattern baldness.

research A Randomized Controlled, Single-Observer Blinded Study to Determine the Efficacy of Topical Minoxidil Plus Microneedling Versus Topical Minoxidil Alone in the Treatment of Androgenetic Alopecia

24 citations, January 2018 in “Journal of Cutaneous and Aesthetic Surgery”

Combining microneedling with minoxidil is more effective for hair growth than using minoxidil alone.

research Microneedling for the Treatment of Hair Loss

58 citations, December 2017 in “Journal of The European Academy of Dermatology and Venereology”

Microneedling can help stimulate hair growth, especially when used with other treatments, but it's not better than existing therapies.

Randomized Trial of Electrodynamic Microneedle Combined with 5% Minoxidil Topical Solution for the Treatment of Chinese Male Androgenetic Alopecia

research Randomized Trial of Electrodynamic Microneedle Combined with 5% Minoxidil Topical Solution for the Treatment of Chinese Male Androgenetic Alopecia

28 citations, October 2017 in “Journal of Cosmetic and Laser Therapy”

Combining electrodynamic microneedle with 5% minoxidil improves hair growth and reduces hair loss in Chinese men.

research Review of Applications of Microneedling in Dermatology

108 citations, August 2017 in “Clinical, Cosmetic and Investigational Dermatology”

Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.

research Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model

55 citations, January 2016 in “Annals of Dermatology”

Microneedle stimulation can increase hair growth in mice.

research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

70 citations, February 2015 in “Expert Opinion on Drug Discovery”

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation

research Dermal β-Catenin Activity in Response to Epidermal Wnt Ligands Is Required for Fibroblast Proliferation and Hair Follicle Initiation

207 citations, March 2012 in “Development”

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

research Androgenetic Alopecia: Clinical Features, Classification, and Treatments

103 citations, June 2007 in “Endocrinology and Metabolism Clinics of North America”

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

research Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp

227 citations, January 1998 in “Journal of Endocrinology”

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Related Research

9 / 9 results

research Effectiveness of Multimodality Therapy Using Minoxidil and Microneedling for the Treatment of Alopecia: A Systematic Review and Meta-Analysis

January 2023

Combining minoxidil with microneedling may be more effective for hair growth than using minoxidil alone.

research Pediatric Androgenetic Alopecia: An Updated Review

January 2023 in “Journal der Deutschen Dermatologischen Gesellschaft”

Early diagnosis and personalized treatment are crucial for managing hair loss in children.

research A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss

1 citations, October 2022 in “PubMed”

Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.

research Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil

1 citations, August 2022 in “JAAD case reports”

Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.

research Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis

1 citations, October 2020 in “Journal of Cosmetic Dermatology”

Using minoxidil and tofacitinib together can effectively treat severe hair loss.

research The Use of Trichoscopy to Assess the Efficacy of Topical Minoxidil 2% Solution in Patients with Female Pattern Hair Loss

April 2019 in “Zagazig university medical journal”

The Efficacy of Topical Minoxidil for Non-Scarring Alopecia: A Systematic Review