Virilization from Partner's Use of Topical Androgen in a Reproductive-Aged Woman
April 2011
in “
American journal of obstetrics and gynecology
”
Studysummary This case report highlights the importance of considering exogenous androgen exposure, such as transdermal testosterone cream used by a partner, in the diagnosis of virilization among women.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
A 22-year-old woman exhibited virilization symptoms, including acne, hirsutism, clitoral enlargement, and scalp alopecia, with elevated testosterone levels but no neoplastic source found on imaging. The cause was later identified as unintentional exposure to her partner's topical testosterone cream. After separating from her partner, her symptoms and testosterone levels normalized. This case underscored the importance of considering exogenous androgen sources in the differential diagnosis of virilization to avoid unnecessary invasive procedures. It also highlighted the need for counseling patients using androgen creams about the risk of transdermal transmission and potential virilization in close contacts.
