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Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Liposomes could improve how skin care products work but are costly and not very stable.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Iontophoresis improves minoxidil delivery for alopecia treatment.

The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.

Nanoemulgel improves hair growth and quality using finasteride without irritation.

Microneedling is effective for skin rejuvenation and various skin issues, but more research is needed to confirm its safety and effectiveness.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

New treatments for male hypogonadism are effective and should be personalized.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

LCN may improve finasteride delivery for hair loss treatment.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.