Detectability of Oxandrolone, Metandienone, Clostebol, and Dehydrochloromethyltestosterone in Urine After Transdermal Application
August 2022
in “
Drug Testing and Analysis
”
Studysummary In this study, transdermal application of anabolic steroids demonstrated rapid and extended detectability in urine, suggesting potential implications for doping control considerations. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated the detectability of four anabolic androgenic steroids (AAS) after transdermal application in 12 male subjects. The substances tested were oxandrolone, metandienone, clostebol, and dehydrochloromethyltestosterone. Urine samples were collected over 14 days and analyzed using GC-MS/MS and LC-MS/MS systems. The results showed that these substances or their metabolites were detectable within hours and remained detectable for up to 10-14 days, with variability in detection windows influenced by individual differences and skin factors. The study concluded that transdermal exposure to these AAS is a plausible scenario in doping, highlighting the need for consideration in anti-doping efforts.
