Adverse Health Effects of Androgen Use

The document reviewed the adverse health effects of anabolic androgenic steroids (AAS), noting that these substances can cause serious and potentially irreversible side effects across multiple organ systems. Cardiovascular issues such as dyslipidemia, arrhythmias, hypertension, and thrombosis were highlighted, along with a dose-dependent increase in left ventricular mass leading to diastolic dysfunction. Neuropsychiatric effects, reproductive issues, liver toxicity, dermatologic problems, musculoskeletal injuries, motor neuron disease implications, and renal issues were also associated with AAS use. The document underscored the importance of physician awareness to counsel patients and the need for public health interventions to address the growing use of AAS. It also detailed the metabolism of AAS, specific organ system effects, and the distrust AAS users have towards physicians, which can impede effective treatment and education.