TLDR Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
Hydrogel-forming microneedles (HFMNs) offer a promising approach for transdermal drug delivery (TDD) by providing a minimally invasive method to penetrate the stratum corneum and deliver drugs effectively without affecting blood vessels and nerves. HFMNs are characterized by their safety, non-toxicity, high drug loading capacity, and controlled drug release, making them suitable for long-term and multiple drug delivery applications. Despite their potential, the transition of HFMNs from research to clinical application faces several challenges. The review highlights the advantages of HFMNs in TDD, their evaluation methods, and their potential applications in disease treatment, emphasizing the need for further development to overcome existing barriers to clinical use.
10 citations
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June 2023 in “Preprints.org” Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
48 citations
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April 2019 in “ACS Applied Materials & Interfaces” A new method for delivering drugs through the skin using biodegradable particles was found to be effective.
140 citations
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December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
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January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
48 citations
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July 2023 in “Biomedicines” Hydrogel-forming microneedles are promising for safe, efficient, and controlled drug delivery through the skin.
140 citations
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December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
64 citations
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May 2019 in “Materials Science and Engineering: C” Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
61 citations
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June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
