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Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Cannabinoids may help treat various skin conditions.

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Stem cells in hair follicles can become various cell types, including neurons.

Topical oligonucleotide therapy targets hair follicles effectively.

GALT5 and GALT2 are important for plant growth and development because they help with protein glycosylation.

A surface with VEGF can specifically capture endothelial cells from flowing fluids.

Stress may trigger hair loss by affecting immune protection in hair follicles.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.

Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.

Notch signaling disruptions can cause various skin diseases.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Testosterone's effects on COVID-19 are unclear and need more research.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

Alopecia areata involves persistent gene abnormalities and immune activity, even in regrown hair, suggesting a risk of relapse.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.