Pleiotropic Role of Notch Signaling in Human Skin Diseases

    Rossella Gratton, Paola Maura Tricarico, Chiara Moltrasio … Sérgio Crovella
    Studysummary This review discusses the role of Notch signaling in skin diseases such as Hidradenitis Suppurativa and Psoriasis, but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 6

    1. JMJD3 and NF-κB-Dependent Activation of Notch1 Gene Is Required for Keratinocyte Migration During Skin Wound Healing Scientific Reports · 2017
    2. Mutations in Gamma-Secretase Subunit-Encoding PSENEN Underlie Dowling-Degos Disease Associated with Acne Inversa Journal of Clinical Investigation · 2017
    3. Anatomy and Function of the Skin Elsevier eBooks · 2016
    4. Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis PloS one · 2011
    5. More Than One Way to Skin Genes & Development · 2008
    6. Epidermal Notch Signaling: Differentiation, Cancer, and Adhesion Current opinion in cell biology · 2008