The Pathobiology of Skin Aging

    April 2020 in “ American Journal Of Pathology ”
    Eleanor Russell‐Goldman, George J. Murphy
    Studysummary This review discusses the multiple factors contributing to skin aging, including cellular changes and environmental influences, and highlights its recognition as a disease with significant implications beyond cosmetic concerns, without reporting new research results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 10

    1. Differential Distribution of the Epigenetic Marker 5-Hydroxymethylcytosine in Hair Follicle Stem Cells During Bulge Activation Journal of Cutaneous Pathology · 2019
    2. Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta Immunity · 2018
    3. Defining Stem Cell Dynamics and Migration During Wound Healing in Mouse Skin Epidermis Nature Communications · 2017
    4. Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin Cold Spring Harbor Perspectives in Medicine · 2014
    5. Synergy of Understanding Dermatologic Disease and Epidermal Biology Journal of Clinical Investigation · 2012
    6. Human Skin Stem Cells and the Aging Process Experimental gerontology · 2008
    7. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    8. The Human Skin as a Hormone Target and an Endocrine Gland Hormones · 2004
    9. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    10. Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001