Cellular Senescence and Aging in Myotonic Dystrophy

    February 2022 in “ International Journal of Molecular Sciences ”
    Yuhei Hasuike, Hidetaka Mochizuki, Mikihito Nakamori
    Studysummary This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 4

    1. Myotonic Dystrophy: A Progeroid Disease? Frontiers in Neurology · 2018
    2. Cutaneous Features of Myotonic Dystrophy Types 1 and 2: Implications of Premature Aging and Vitamin D Homeostasis Neuromuscular Disorders · 2016
    3. Directed Elimination of Senescent Cells by Inhibition of BCL-W and BCL-XL Nature communications · 2016
    4. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated With p16INK4a Expression Journal of Investigative Dermatology · 2007

    Related research 1

    1. Cellular Senescence and Aging in Myotonic Dystrophy International Journal of Molecular Sciences · 2022