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    Did you mean Myotonic Dystrophy Type 1?
    Glossary Myotonic Dystrophy Type 1

    genetic disorder causing progressive muscle wasting and weakness

    Myotonic Dystrophy Type 1 (DM1), also known as Steinert disease, is a genetic disorder characterized by progressive muscle wasting and weakness. It is caused by a mutation in the DMPK gene, leading to an abnormal expansion of DNA repeats that disrupts normal cellular function. Symptoms can include muscle stiffness (myotonia), cataracts, heart conduction defects, and endocrine changes, and the severity can vary widely among individuals.

    Research 10 of 75

    1. Myotonic Dystrophy—A Progeroid Disease? Frontiers in Neurology · 2018 · 41 citations
    2. Dysplastic nevi, cutaneous melanoma, and other skin neoplasms in patients with myotonic dystrophy type 1: A cross-sectional study Journal of The American Academy of Dermatology · 2015 · 23 citations
    3. Multiple pigmentierte Basaliome im Capillitium bei Myotonia dystrophia Curschmann-Steinert Der Hautarzt · 2001 · 18 citations
    4. Cutaneous features of myotonic dystrophy types 1 and 2: Implication of premature aging and vitamin D homeostasis Neuromuscular Disorders · 2016 · 18 citations
    5. Three cases of androgen‐dependent disease associated with myotonic dystrophy 2003 · 8 citations
    6. Skin features in myotonic dystrophy type 1: An observational study Neuromuscular Disorders · 2015 · 8 citations
    7. Late presentation of myotonic dystrophy Clinical and experimental dermatology · 1998 · 5 citations
    8. Cellular Senescence and Aging in Myotonic Dystrophy International Journal of Molecular Sciences · 2022 · 4 citations
    9. Multiple basal cell carcinomas in a patient with myotonic dystrophy type 1 Case Reports · 2019 · 3 citations
    10. SAT-510 Association of Myotonic Dystrophy with Autoimmune Endocrinopathies and Thyroid Carcinoma Journal of the Endocrine Society · 2020
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