Three Cases of Androgen-Dependent Disease Associated with Myotonic Dystrophy

    January 2003 in “ JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology ”
    S. M. Cooper, R.P.R. Dawber, David Hilton‐Jones
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    TLDR Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.
    The document describes three cases where females with myotonic dystrophy, a condition typically associated with lower serum androgen levels compared to normal controls, developed androgen-dependent diseases such as acne, hidradenitis suppurativa, androgenetic alopecia, and keratosis pilaris. These cases suggest that the sensitivity of body tissues to androgens, rather than the absolute levels of circulating androgens, plays a significant role in the development of androgen-dependent conditions.
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