Male Fertility and Skin Diseases

The document from 2016 examines the impact of skin diseases and their treatments on male fertility. It notes that while the prevalence of skin diseases causing infertility is low, they can affect fertility at various levels and their management is complex. Severe skin diseases are linked to semen abnormalities, and several genodermatoses and acquired skin diseases, including infections, autoimmune diseases, and malignancies, can impair male reproductive health. Treatments like cytotoxic drugs, irradiation, and antiandrogens also affect fertility, with some effects being reversible. The paper details specific genetic syndromes associated with infertility, such as LEOPARD syndrome, McCune-Albright syndrome, and Rothmund-Thomson syndrome, among others. It emphasizes the importance of early treatment and the need for more research to understand these associations fully.