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GlossaryMalignancies

abnormal cell growths that invade and spread, causing cancer

Malignancies, also known as malignant tumors or malignant neoplasms, are abnormal growths of cells that have the potential to invade and destroy surrounding tissues and spread to other parts of the body (metastasize). Unlike benign tumors, which are non-cancerous and do not spread, malignancies are cancerous and can be life-threatening if not treated promptly.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program

research Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program

January 2024 in “American journal of clinical dermatology”

Ritlecitinib is safe and well-tolerated for treating alopecia areata in patients aged 12 and older.

Baricitinib Safety for Events of Special Interest in Populations at Risk: Analysis from Randomised Trial Data Across Rheumatologic and Dermatologic Indications

research Baricitinib Safety for Events of Special Interest in Populations at Risk: Analysis from Randomised Trial Data Across Rheumatologic and Dermatologic Indications

6 citations , February 2023 in “Advances in Therapy”

Baricitinib, a drug for rheumatoid arthritis, atopic dermatitis, and alopecia areata, is generally safe with low risk of major side effects, even in patients with risk factors. It's also effective in promoting hair regrowth in alopecia areata patients.

research Male Fertility and Skin Diseases

12 citations , June 2016 in “Reviews in Endocrine and Metabolic Disorders”

Some skin diseases and their treatments can negatively affect male fertility.

research Alopecia as a Systemic Disease

7 citations , July 2019 in “Clinics in Dermatology”

Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.

Cyclophosphamide: As Bad as Its Reputation? Long-Term Single Centre Experience of Cyclophosphamide Side Effects in the Treatment of Systemic Autoimmune Diseases

research Cyclophosphamide: As Bad as Its Reputation? Long-Term Single Centre Experience of Cyclophosphamide Side Effects in the Treatment of Systemic Autoimmune Diseases

39 citations , October 2014 in “Schweizerische medizinische Wochenschrift”

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

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community Anageninc no longer sell KX-826 (Pyrilutamide) due to receiving a cease and desist letter from Kintor :(

in Update 19 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Anageninc stopped selling KX-826 (Pyrilutamide) due to a cease and desist letter from Kintor, but this may indicate promising study results and a potential 2024 release.

community What else is good. Besides the big 3.

in Chat 35 upvotes 1 year ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.