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Glossary Malignancies

abnormal cell growths that invade and spread, causing cancer

Malignancies, also known as malignant tumors or malignant neoplasms, are abnormal growths of cells that have the potential to invade and destroy surrounding tissues and spread to other parts of the body (metastasize). Unlike benign tumors, which are non-cancerous and do not spread, malignancies are cancerous and can be life-threatening if not treated promptly.

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research Paraneoplastic alopecia associated with internal malignancies in the cat

48 citations , March 1997 in “Veterinary Dermatology”

This report describes a paraneoplastic alopecia in four cats associated with internal malignancy, confirming previous findings of a syndrome linking ventral alopecia and metastatic carcinomas.

research The use of minoxidil to attempt to prevent alopecia during chemotherapy for gynecologic malignancies.

36 citations , January 1991 in “PubMed”

In this pilot study, 2% topical Minoxidil showed no benefit in preventing hair loss during chemotherapy for gynecologic cancers, although it was non-toxic.

research Alopecia Areata and malignancies: uncertainties clarified by a large-scale population-based study

3 citations , October 2024 in “Archives of Dermatological Research”

This study found that alopecia areata was associated with an increased risk of hematological malignancies, particularly non-Hodgkin lymphoma, but not with solid malignancies, except in certain severe cases.

research Risk of estrogen-driven malignancies in females on 5-alpha reductase inhibitors

1 citations , November 2024 in “Archives of Dermatological Research”

research Sacituzumab Tirumotecan Across Gynecologic Malignancies: One Target, Multiple Diseases

June 2026 in “Current Oncology Reports”

This review highlights the potential of Sacituzumab Tirumotecan, an antibody-drug conjugate, in treating gynecologic cancers, with ongoing Phase III trials indicating a manageable safety profile and future results expected to shed light on its effectiveness in improving survival and response rates.

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