Dermatologic Aspects of Male Hypogonadism

    January 2000 in “ Der Hautarzt ”
    F.‐M. Köhn, Joshua Ring, Wolf‐Bernhard Schill
    TLDR Male hypogonadism affects skin and hair, causing thin skin, less hair, and skin reactions to treatment.
    Male hypogonadism was associated with several dermatological features due to its androgen-dependent nature. Patients exhibited thin skin with increased wrinkles, reduced hair growth in various areas, and a lack of pigmentation in genital skin. Prepubertal hypogonadism did not lead to severe acne but resulted in sebostasis. Typical androgenetic alopecia was not observed. Treatment for hypogonadism could cause dermatological diseases, with irritative or allergic skin reactions being common, particularly with non-scrotal transdermal testosterone systems. Although various syndromes included dermatological symptoms linked to male hypogonadism, their prevalence was low.
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