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This review examines the pathogenesis of androgen excess and dyslipidemia in PCOS and the potential role of statins as a treatment but provides no new clinical results.

This animal study observed that dihydrotestosterone increased arterial stiffness and decreased estrogen receptor expression in female mice, potentially impacting cardiovascular health in contexts of androgen use.

This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.

In this case report, a 55-year-old postmenopausal woman was diagnosed with ovarian hyperthecosis as the cause of her hyperandrogenism after detailed hormonal and imaging investigations, which was successfully treated with bilateral salpingo-oophorectomy, leading to symptom improvement and normalized testosterone levels.

In this case study, researchers observed a 5.8-year-old male with peripheral precocious puberty due to a germ cell tumor, marked by elevated human chorionic gonadotropin levels. Treatment normalized hormone levels and arrested the puberty progression, highlighting melatonin's potential role in transitions to central precocious puberty.

This book chapter reviews the genetic and epigenetic factors influencing PCOS, particularly in a global context and specific to India, and reports no new clinical findings.

This study observed that in a mouse model of androgenetic alopecia, treatments with LTF, 5% minoxidil, and LTF-DPC-EXO significantly promoted hair regeneration compared to the model group, potentially through modulation of the PI3K/AKT signaling pathway.

In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.

This systematic review reported that gender-affirming hormone therapy may lead to changes in hair growth patterns, with differing effects for transgender men and women, potentially impacting quality of life.

This case report highlights the need for early diagnosis and treatment of ovarian hyperthecosis to enhance the quality of life and health outcomes for affected patients.

This case report highlights the importance of considering an ovarian steroid cell tumor diagnosis in young women with increased testosterone after ruling out polycystic ovarian syndrome.

This study suggests that a mixture of Chrysanthemum zawadskii, peppermint, and Glycyrrhiza glabra promotes hair growth and reduces hair loss markers in testosterone-treated cells and mice.

This study found that hirsutism, acne, acanthosis nigricans, and seborrheic dermatitis may serve as reliable cutaneous indicators of PCOS in women.

This case report describes a 29-year-old female with resistant polycystic ovary syndrome who experienced symptom relief following a unilateral oophorectomy.

This article reviews various discoveries about hair follicle cycles, androgenic alopecia, and the role of dihydrotestosterone, emphasizing the effectiveness of hair transplantation and reports no new findings.

This study found that extracellular vesicles derived from hyaluronic acid-stimulated induced pluripotent stem cells significantly improved hair growth in a model of androgenetic alopecia in mice by enhancing Wnt/β-catenin signaling and regulating androgen receptor activity, showing comparable results to the commonly used treatment finasteride.

This study found that administering melatonin for 12 weeks to women with PCOS significantly reduced hirsutism, testosterone, and inflammation markers, while enhancing antioxidant levels compared to a placebo.

This study describes molecular mechanisms explaining how sex and stress steroids rapidly modulate dendritic spine formation in hippocampal neurons, suggesting recovery-like effects under steroid-depleted conditions compared to intact conditions.

In this study, treatment with flutamide combined with a low-dose oral contraceptive significantly improved hirsutism in women with polycystic ovarian disease who did not respond to oral contraceptive treatment alone.

This review discusses the role of sex hormones in COVID-19 severity and reports no new clinical results; the authors suggest further research for gender-based personalized treatment options.

This study suggested that moxibustion treatment before or at the early stage of diminished ovarian reserve in rats may improve ovarian function by modulating androgen balance, though its effects differ across intervention timings.

This study found that Henna had the most pronounced effect on hair growth in a mouse model of androgenetic alopecia, possibly by reducing local androgen content.

Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.

This study found that the GPRC6A-Duox1 signaling pathway influences hair cycle progression and testosterone-mediated hair loss in mice, suggesting that disruption of this pathway leads to resistance against testosterone-induced hair loss and longer anagen phase duration.

This study found that blocking the chemokine CXCL12 in a testosterone-induced mouse model of androgenetic alopecia restored hair regeneration and reduced fibrosis and immune alterations.

This review discusses the degenerative effects of anabolic-androgenic steroids on the nervous system and reports no new experimental results, aiming to increase public awareness of their health risks.

This review examines biological reasons for sex-based differences in COVID-19 outcomes, noting that females exhibit stronger immune responses, potentially explaining lower severity and mortality compared to males.

This study found that lower salmon availability was associated with higher stress hormone levels in grizzly and black bears, influencing their physiological responses and competitive behaviors.

This review discusses the relationship between polycystic ovary syndrome and inflammation, highlighting various inflammatory markers, but reports no new clinical results.

In this study using rat hippocampal cultures, progesterone and testosterone showed neuroprotective effects against oxygen-glucose deprivation-induced neuronal cell death, while metabolism of these hormones in the brain may affect their protective actions.