Treatment of Hirsutism with Flutamide and a Low-Dosage Oral Contraceptive in Polycystic Ovarian Disease Patients

December 1994 in “ Fertility and sterility ”

L Ciotta, Antonio Cianci, Elvira Marletta, Laura Pisana, Anna Maria Aglianò, Giuseppe Palumbo

Studysummary In this study, treatment with flutamide combined with a low-dose oral contraceptive significantly improved hirsutism in women with polycystic ovarian disease who did not respond to oral contraceptive treatment alone.

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This study found that an 8-month treatment with a low-dose oral contraceptive significantly reduced testosterone levels and hair growth in women with polycystic ovary syndrome and hirsutism, with minimal side effects.