Finasteride And Flutamide In The Treatment Of Hirsutism
October 1997
in “
PubMed
”
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Studysummary This study found that both finasteride and flutamide significantly decreased hirsutism severity and hair diameter in women with PCOS and Idiopathic Hirsutism, with abdominal hairs showing greater sensitivity to the treatments.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
In a study conducted 25 years ago, 80 hirsute patients, 44 with Polycystic Ovary Syndrome (PCOS) and 36 with Idiopathic Hirsutism (IH), were treated with two antiandrogen drugs, finasteride and flutamide, to evaluate their efficacy. The patients were randomly assigned to receive either finasteride (5 mg/daily) or flutamide (250 mg twice daily) for 6 consecutive months. Both finasteride and flutamide significantly reduced the Ferriman Gallway score (a measure of hirsutism) and hair diameter, indicating their effectiveness in treating hirsutism. The study also found that abdominal hairs were more sensitive to the therapy.
