Antiandrogen Treatment of Polycystic Ovary Syndrome

    Roger S. Rittmaster
    Studysummary This review concludes that antiandrogens with ovarian suppression may significantly improve hirsutism and androgenetic alopecia in women with PCOS, but treatment needs to continue unless the underlying PCOS cause is addressed.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 22

    1. Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism Journal of Endocrinological Investigation · 1998
    2. Hair Regrowth Dermatologic Clinics · 1998
    3. Comparison of Finasteride Versus Spironolactone in the Treatment of Idiopathic Hirsutism Fertility and Sterility · 1997
    4. Gonadotrophin-Releasing Hormone Agonist Therapy for Hirsutism Is as Effective as High Dose Cyproterone Acetate but Results in a Longer Remission Human reproduction · 1997
    5. Clinical Updates in Hair Dermatologic Clinics · 1997
    6. Treatment of Hirsutism by Finasteride and Flutamide in Women with Polycystic Ovary Syndrome Gynecological Endocrinology · 1997
    7. Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up Fertility and Sterility · 1996
    8. Finasteride in the Treatment of Hirsutism: New Therapeutic Perspectives Fertility and Sterility · 1996
    9. A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1995
    10. Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994
    11. Drug-Induced Hair Loss and Hair Growth Drug Safety · 1994
    12. Comparison of Flutamide and Spironolactone in the Treatment of Hirsutism: A Randomized Controlled Trial Fertility and Sterility · 1994
    13. Cyproterone Acetate for Severe Hirsutism: Results of a Double-Blind Dose-Ranging Study Clinical endocrinology · 1991
    14. Comparison of Sequential Cyproterone Acetate/Estrogen Versus Spironolactone/Oral Contraceptive in the Treatment of Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1991
    15. Effect of Leuprolide and Dexamethasone on Hair Growth and Hormone Levels in Hirsute Women: The Relative Importance of the Ovary and the Adrenal in the Pathogenesis of Hirsutism The Journal of Clinical Endocrinology & Metabolism · 1990
    16. Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers The Journal of Clinical Endocrinology and Metabolism · 1990
    17. Side Effects of Spironolactone Therapy in the Hirsute Woman ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1988
    18. Regulation of Androgen Receptor and 5α-Reductase in the Skin of Normal and Hirsute Women Clinics in endocrinology and metabolism · 1986
    19. Treatment of Hirsutism and Acne with Cyproterone Acetate Clinics in Endocrinology and Metabolism · 1986
    20. The Effects of Two Doses of Spironolactone on Serum Androgens and Anagen Hair in Hirsute Women Fertility and sterility · 1985
    21. Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex British Journal of Dermatology · 1977
    22. Use of Cyproterone Acetate in the Treatment of Acne, Hirsutism, and Virilism Journal of Steroid Biochemistry · 1975

    Related research 5

    1. Dermatology of Androgen-Related Disorders Clinics in Dermatology · 2006
    2. Antiandrogen Treatment of Polycystic Ovary Syndrome Endocrinology and Metabolism Clinics of North America · 1999
    3. Other Antiandrogens: Alternative Treatments for Acne and Hirsutism Dermatology · 1998
    4. The Antiandrogens Dermatologic Clinics · 1993
    5. The Antiandrogens: When And How They Should Be Used PubMed · 1993