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    GlossaryEstradiol (E2)

    potent estrogen hormone primarily produced in the ovaries

    Estradiol, also known as 17β-Estradiol or E2, is a potent estrogen hormone primarily produced in the ovaries. It plays a crucial role in regulating the menstrual cycle, reproductive system, and secondary sexual characteristics in females. Additionally, estradiol has significant effects on various tissues, including bone, skin, and hair, influencing growth and maintenance.

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      An essential vasodilator with some anti-androgenic effects, has excellent safety record

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      community What to do about High E2 levels on Finasteride?

      in Treatment  6 upvotes 2 years ago
      User experienced high E2 levels after taking finasteride and sought advice on lowering E2 with supplements like Tonkat ali, Fadogia, and Boron. They also used DIM, zinc, and magnesium but avoided using an AI.

      community Castor Oil - Yay or Nay?

      in Product  10 upvotes 3 years ago
      The conversation discusses the potential benefits of castor oil for hair thickening, with one user noting it may increase prostaglandin E2 and decrease PGD2. The original poster plans to take 1-2ml orally daily.

      community Blood work after 4 month topical fin/min

      in Update  6 upvotes 3 months ago
      After 4 months of using topical finasteride and minoxidil, blood tests showed increased E2, Test, and Prolactine levels. The user is concerned about potential side effects like gyno and is seeking advice on managing these values.

      community Does it work? Maneup GHK-Cu hair growth serum

      in Treatment  8 upvotes 7 months ago
      The conversation is about the effectiveness of Maneup GHK-Cu hair growth serum, a topical treatment for hair loss. The user is considering trying it but is skeptical due to issues others have had with DIY injections of a similar substance.